详情页 - 聚合机构库演示平台

当前位置：首页 > 详情页

The role of GTPase-activating protein ARHGAP26 in human cancers.

文献详情

资源类型：

Pubmed体系：

作者：

单位： [1]Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, National Clinical Research Center for Digestive Diseases, Beijing Digestive Disease center, Beijing Key Laboratory for Precancerous Lesion of Digestive Diseases, Beijing, China. [2]Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, National Clinical Research Center for Digestive Diseases, Beijing Digestive Disease center, Beijing Key Laboratory for Precancerous Lesion of Digestive Diseases, Beijing, China. lipeng@ccmu.edu.cn. [3]Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, National Clinical Research Center for Digestive Diseases, Beijing Digestive Disease center, Beijing Key Laboratory for Precancerous Lesion of Digestive Diseases, Beijing, China. zhangshutian@ccmu.edu.cn.

出处：

DOI：

ISSN：

摘要：

Rho GTPases are molecular switches that play an important role in regulating the behavior of a variety of tumor cells. RhoA GTPase-activating protein 26 (ARHGAP26) is a GTPase-activating protein and inhibits the activity of Rho GTPases by promoting the hydrolytic ability of Rho GTPases. It also affects tumorigenesis and progression of various tumors through several methods, including formation of abnormal fusion genes and circular RNA. This review summarizes the biological functions and molecular mechanisms of ARHGAP26 in different tumors, proposes the potential clinical value of ARHGAP26 in cancer treatment, and discusses current issues that need to be addressed.© 2021. The Author(s).

语种：

PubmedID：

中科院(CAS)分区：

出版当年[2020]版：

大类 | 3 区生物

小类 | 4 区细胞生物学

最新[2025]版：

大类 | 3 区生物学

小类 | 3 区细胞生物学

JCR分区：

出版当年[2019]版：

Q3 CELL BIOLOGY

最新[2023]版：

Q3 CELL BIOLOGY

影响因子： 最新[2023版] 3.5 最新五年平均[2021-2025] 3.3 出版当年[2019版] 2.795 出版当年五年平均[2015-2019] 2.681 出版前一年[2018版] 2.884 出版后一年[2020版] 3.396

第一作者：

第一作者单位： [1]Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, National Clinical Research Center for Digestive Diseases, Beijing Digestive Disease center, Beijing Key Laboratory for Precancerous Lesion of Digestive Diseases, Beijing, China.

推荐引用方式(GB/T 7714)：

APA：

MLA：