单位:[1]Department of Dermatology, China–Japan Friendship Hospital, Beijing, China,[2]Graduate School of Peking Union Medical College, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
The skin is the outermost barrier of the body. It has developed a sophisticated system against the ever-changing environment. The application of single-cell technologies has revolutionized dermatology research and unraveled the changes and interactions across skin resident cells in the healthy and inflamed skin. Single-cell technologies have revealed the critical roles of stromal cells in an inflammatory response and explained a series of plausible previous findings concerning skin immunity. Here, we summarized the functional diversity of skin stromal cells defined by single-cell analyses and how these cells orchestrated events leading to inflammatory diseases, including atopic dermatitis, psoriasis, vitiligo, and systemic lupus erythematosus.
基金:
This work was supported by the National Natural Science
Foundation of China (Grant No. 81872516, 82173418, and
82103100).
第一作者单位:[1]Department of Dermatology, China–Japan Friendship Hospital, Beijing, China,[2]Graduate School of Peking Union Medical College, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
通讯作者:
通讯机构:[1]Department of Dermatology, China–Japan Friendship Hospital, Beijing, China,[2]Graduate School of Peking Union Medical College, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
推荐引用方式(GB/T 7714):
Liu Baoyi,Li Ang,Xu Jingkai,et al.Single-Cell Transcriptional Analysis Deciphers the Inflammatory Response of Skin-Resident Stromal Cells[J].FRONTIERS in SURGERY.2022,9:doi:10.3389/fsurg.2022.935107.
APA:
Liu, Baoyi,Li, Ang,Xu, Jingkai&Cui, Yong.(2022).Single-Cell Transcriptional Analysis Deciphers the Inflammatory Response of Skin-Resident Stromal Cells.FRONTIERS in SURGERY,9,
MLA:
Liu, Baoyi,et al."Single-Cell Transcriptional Analysis Deciphers the Inflammatory Response of Skin-Resident Stromal Cells".FRONTIERS in SURGERY 9.(2022)