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Prevalence and burden of chronic cough in China: a national cross-sectional study

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单位: [1]Beijing Key Laboratory of Respiratory and Pulmonary Circulation Disorders, Dept of Pulmonary and Critical Care Medicine, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China. [2]Beijing Institute of Respiratory Medicine, Beijing, China. [3]National Center for Respiratory Medicine, National Clinical Research Center for Respiratory Diseases, Beijing, China. [4]Dept of Pulmonary and Critical Care Medicine, China-Japan Friendship Hospital, Beijing, China. [5]Institute of Respiratory Medicine, Chinese Academy of Medical Sciences, Beijing, China. [6]Dept of Respiratory Medicine, Capital Medical University, Beijing, China. [7]Dept of Pulmonary and Critical Care Medicine, Shanxi Bethune Hospital, Taiyuan, China. [8]Dept of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China. [9]Dept of Pulmonary and Critical Care Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. [10]Dept of Pulmonary and Critical Care Medicine, Guizhou Provincial People's Hospital, Guiyang, China. [11]Dept of Pulmonary and Critical Care Medicine, Zhongshan Hospital, Fudan University, Shanghai, China. [12]Dept of Pulmonary and Critical Care Medicine, The First Hospital of China Medical University, Shenyang, China. [13]State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Diseases, Guangzhou Institute of Respiratory Diseases, The First Affiliated Hospital, Guangzhou Medical University, Guangzhou, China. [14]Dept of Respiratory and Critical Care Medicine, The Second Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou, China. [15]State Key Laboratory of Biotherapy of China and Dept of Respiratory and Critical Care Medicine, West China Hospital of Sichuan University, Chengdu, China. [16]Dept of Respiratory and Critical Care Medicine, Peking University Third Hospital, Beijing, China. [17]Dept of Respiratory and Critical Care Medicine, Beijing Hospital, Beijing, China. [18]National Center of Gerontology, Beijing Hospital, Beijing, China. [19]Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences. School of Basic Medicine, Peking Union Medical College, Beijing, China. [20]Center for Clinical Epidemiology and Evidence-based Medicine, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China. [21]WHO Collaborating Center for Tobacco Cessation and Respiratory Diseases Prevention, Beijing, China. [22]Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, USA. [23]National Heart &amp. Lung Institute, Imperial College London, and Royal Brompton &amp. Harefield NHS Trust, London, UK. [24]Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
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Chronic cough is a common complaint, but there are no population-based data on its burden in China. We determined the prevalence of chronic cough and its impact on health status in adults stratified by sex, age and the diagnosis of COPD or the presence of small airway dysfunction (SAD).A representative sample of 57 779 Chinese adults aged 20 years or older was recruited and pulmonary function test was measured. Chronic cough was defined as cough lasting for >3 months in each year. Quality of life was assessed by the 12-item Short Form Health Survey (SF-12), and self-reported history of hospital visits was recorded.Chronic cough was found in 3.6% (95% CI 3.1-4.1) of Chinese adults, 2.4% (95% CI 1.9-3.1) of those aged 20-49 years and 6.0% (95% CI 5.3-6.8) of those aged 50 years or older. Individuals with chronic cough had an impaired physical component summary (PCS) score of the SF-12 (p<0.0001) and more emergency visits (p=0.0042) and hospital admissions (p=0.0002). Furthermore, the impact of chronic cough on PCS score was more significant in those aged 50 years or older, or with COPD (p=0.0018 or 0.0002, respectively), with the impact on hospital admission being more significant in those with COPD or with SAD (p=0.0026 or 0.0065, respectively).Chronic cough is prevalent in China and is associated with a poorer health status, especially in individuals aged 50 years or older and those with the diagnosis of COPD or SAD.Copyright ©The authors 2022.

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大类 | 2 区 医学
小类 | 3 区 呼吸系统
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Q1 RESPIRATORY SYSTEM

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第一作者:
第一作者单位: [1]Beijing Key Laboratory of Respiratory and Pulmonary Circulation Disorders, Dept of Pulmonary and Critical Care Medicine, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China. [2]Beijing Institute of Respiratory Medicine, Beijing, China.
通讯作者:
通讯机构: [3]National Center for Respiratory Medicine, National Clinical Research Center for Respiratory Diseases, Beijing, China. [4]Dept of Pulmonary and Critical Care Medicine, China-Japan Friendship Hospital, Beijing, China. [5]Institute of Respiratory Medicine, Chinese Academy of Medical Sciences, Beijing, China. [6]Dept of Respiratory Medicine, Capital Medical University, Beijing, China. [21]WHO Collaborating Center for Tobacco Cessation and Respiratory Diseases Prevention, Beijing, China. [24]Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
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