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Evaluating the predictive value of diabetes mellitus diagnosed according to the Chinese guidelines (2020 edition) for cardiovascular events

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单位: [1]Peking Univ, Dept Cardiol, China Japan Friendship Sch Clin Med, Beijing 100029, Peoples R China [2]China Japan Friendship Hosp, Dept Cardiol, 2 Yinghua Dongjie, Beijing 100029, Peoples R China [3]Chinese Acad Med Sci & Peking Union Med Coll, Grad Sch, Peking Union Med Coll, Beijing 100029, Peoples R China
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关键词: Cardiovascular disease Diabetes Chinese guideline Predictive value Adults

摘要:
Objective Chinese diabetes society has published the new diagnostic criteria for diabetes in China (2020 edition). We aimed to investigate the predictive value of new diabetes-diagnosed criteria for cardiovascular diseases (CVD). Methods A total of 5884 individuals from the China Health and Retirement Longitudinal Study in 2011 and 2018 were enrolled. Baseline characteristics and outcome data were compared. The association between diabetes diagnosed by two criteria and future CVD was identified by Kaplan-Meier curves, Cox regression analyses, and receiver-operating characteristic analyses. Delong's test was conducted to compare the predictive value for future CVD between diabetes diagnosed by the 2020 edition and diabetes diagnosed by the previous version. Results After multivariate adjustment, both diabetes diagnosed by the 2020 edition and diabetes diagnosed by the previous edition is associated with CVD (HR 1.607, 95% CI 1.221-2.115, P < 0.001; HR 1.244, 95% CI 1.060-1.460, P = 0.007, respectively). The Kaplan-Meier analysis indicated that diabetes patients have more cardiovascular risk (log-rank P<0.001). Moreover, diabetes diagnosed in the 2020 edition illustrated an area under the curve (AUC) of 0.673 for predicting CVD, while diabetes diagnosed in the previous edition showed an AUC of 0.638 (DeLong's test P<0.01). Conclusion Diabetes diagnosis criteria (2020 edition) in China had better performance in predicting cardiovascular diseases than the previous edition.

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中科院(CAS)分区:
出版当年[2021]版:
大类 | 4 区 医学
小类 | 4 区 内分泌学与代谢
最新[2025]版:
大类 | 3 区 医学
小类 | 3 区 内分泌学与代谢
JCR分区:
出版当年[2020]版:
Q3 ENDOCRINOLOGY & METABOLISM
最新[2023]版:
Q2 ENDOCRINOLOGY & METABOLISM

影响因子: 最新[2023版] 最新五年平均[2021-2025] 出版当年[2020版] 出版当年五年平均[2016-2020] 出版前一年[2019版] 出版后一年[2021版]

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第一作者单位: [1]Peking Univ, Dept Cardiol, China Japan Friendship Sch Clin Med, Beijing 100029, Peoples R China
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通讯机构: [1]Peking Univ, Dept Cardiol, China Japan Friendship Sch Clin Med, Beijing 100029, Peoples R China [2]China Japan Friendship Hosp, Dept Cardiol, 2 Yinghua Dongjie, Beijing 100029, Peoples R China
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