单位：[1]Department of Anesthesiology, Beijing Jishuitan Hospital, People’s Republic of China[2]Department of Neurological Surgery and Brain Repair, Morsani College of Medicine, University of South Florida, Tampa, USA[3]Department of Anesthesiology, Xuanwu Hospital, Capital Medical University, Beijing, People’s Republic of China首都医科大学宣武医院[4]Department of Physiology & Pharmacology, Loma Linda University School of Medicine, USA[5]Department of Anesthesiology, Loma Linda University School of Medicine, USA[6]Department of Anesthesiology, Beijing Friendship Hospital, Capital Medical University, People’s Republic of China临床科室麻醉科麻醉科首都医科大学附属北京友谊医院
Ganglioside GM1 is a member of the ganglioside family which has been used in many countries and is thought of as a promising alternative treatment for preventing several neurological diseases, including cerebral ischemic injury. The therapeutic effects of GM1 have been proved both in neonates and in adults following ischemic brain damage; however, its clinical efficacy in patients with ischemic stroke is still uncertain. This review examines the recent knowledge of the neuroprotective properties of GM1 in ischemic stroke, collected in the past two decades. We conclude that GM1 may have potential for stroke treatment, although we need to be cautious in respect of its complications.
基金：
National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81500996]; Beijing Jishuitan Hospital Nova Program [xkxx201619]; National Clinical Research for Geriatric Disorders, Xuanwu Hospital of Capital Medical University [20170026]
语种：
外文
被引次数：
WOS：
PubmedID：
中科院(CAS)分区：
出版当年[2018]版：
大类|3 区医学
小类|3 区医学：研究与实验3 区移植4 区细胞与组织工程
最新[2025]版：
大类|4 区医学
小类|3 区移植4 区细胞与组织工程4 区医学：研究与实验
JCR分区：
出版当年[2017]版：
Q2MEDICINE, RESEARCH & EXPERIMENTALQ2TRANSPLANTATIONQ3CELL & TISSUE ENGINEERING
最新[2023]版：
Q2MEDICINE, RESEARCH & EXPERIMENTALQ2TRANSPLANTATIONQ3CELL & TISSUE ENGINEERING
第一作者单位：[1]Department of Anesthesiology, Beijing Jishuitan Hospital, People’s Republic of China
通讯作者：
通讯机构：[4]Department of Physiology & Pharmacology, Loma Linda University School of Medicine, USA[6]Department of Anesthesiology, Beijing Friendship Hospital, Capital Medical University, People’s Republic of China[*1]Department of Physiology & Pharmacology, Loma Linda University School of Medicine, Loma Linda, CA, USA.[*2]Department of Anesthesiology, Beijing Friendship Hospital, Capital Medical University, No.95 Yong-An Road, Xi-Cheng District, Beijing 100050, People Republic of China
推荐引用方式(GB/T 7714)：
Zhang Wenchao,Krafft Paul R.,Wang Tianlong,et al.Pathophysiology of Ganglioside GM1 in Ischemic Stroke: Ganglioside GM1: A Critical Review[J].CELL TRANSPLANTATION.2019,28(6):657-661.doi:10.1177/0963689718822782.
APA：
Zhang, Wenchao,Krafft, Paul R.,Wang, Tianlong,Zhang, John H.,Li, Li&Tang, Jiping.(2019).Pathophysiology of Ganglioside GM1 in Ischemic Stroke: Ganglioside GM1: A Critical Review.CELL TRANSPLANTATION,28,(6)
MLA：
Zhang, Wenchao,et al."Pathophysiology of Ganglioside GM1 in Ischemic Stroke: Ganglioside GM1: A Critical Review".CELL TRANSPLANTATION 28..6(2019):657-661
