单位：[1]Department of Epidemiology & Biostatistics, School of Public Health, Zhejiang University, Hangzhou 310058, China[2]Department of Nutrition, School of Public Health, Zhejiang University, Hangzhou 310058, China[3]Shanghai Diabetes Institute, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai 200233, China[4]Department of Endocrinology, Sir Run Run Shaw Hospital, Affiliated to School of Medicine, Zhejiang University, Hangzhou 310016, Zhejiang, China[5]Department of Endocrinology and Metabolism, The First Affiliated Hospital, China Medical University, Beier Road No. 92, Shenyang 110001, China[6]Department of Endocrinology, China-Japan Friendship Hospital, Beijing 100029, China[7]Department of Endocrinology and Diabetes Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, China院本部南沙医院内科内分泌内科内科内分泌内科中山大学附属第一医院[8]Department of Endocrinology and Metabolism, West China Hospital, Sichuan University, Chengdu 610041, Sichuan, China四川大学华西医院[9]Department of Chronic and Noncommunicable Disease Control and Prevention, Hangzhou Center for Disease Control and Prevention, Hangzhou 310021, China[10]Department of Pathology, Zhejiang University School of Medicine, Hangzhou 310058, China
Background: The study was to investigate the prevalence of metabolic health in subjects with obesity in the Chinese population and to identify the determinants related to metabolic abnormality in obese individuals. Methods: 5013 subjects were recruited from seven provincial capitals in China. The obesity and metabolic status were classified based on body mass index (BMI) and the number of abnormalities in common components of metabolic syndrome. Results: 27.9% of individuals with obesity were metabolically healthy. The prevalence of the metabolically healthy obese (MHO) phenotype was significantly decreased with age in women (p(trend) < 0.001), but not significantly in men (p(trend) = 0.349). Central obesity (odds ratio [OR] = 4.07, 95% confidence interval [CI] = 1.93-8.59), longer sedentary time (OR = 1.97, 95%CI = 1.27-3.06), and with a family history of obesity related diseases (hypertension, diabetes, dyslipidemia) (OR = 1.85, 95%CI = 1.26-2.71) were significantly associated with having metabolic abnormality in obese individuals. Higher levels of physical activity and more fruit/vegetable intake had decreased ORs of 0.67 (95%CI = 0.45-0.98) and 0.44 (95%CI = 0.28-0.70), respectively. Conclusion: 27.9% of obese participants are in metabolic health. Central obesity, physical activity, sedentary time, fruits/vegetables intake and family history of diseases are the determinants associated with metabolic status in obesity.
基金：
National Key Technology R&D Program of ChinaNational Key Technology R&D Program [2012BAI02B03]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81172755, 81102200]; Fundamental Research Funds for the Central Universities and Program for Zhejiang Leading Team of Science and Technology Innovation [2010R50050]; Zhejiang Provincial Program for the Cultivation of High-Level Innovative Health Talents
第一作者单位：[1]Department of Epidemiology & Biostatistics, School of Public Health, Zhejiang University, Hangzhou 310058, China
共同第一作者：
通讯作者：
推荐引用方式(GB/T 7714)：
Ruizhi Zheng,Min Yang,Yuqian Bao,et al.Prevalence and Determinants of Metabolic Health in Subjects with Obesity in Chinese Population[J].INTERNATIONAL JOURNAL of ENVIRONMENTAL RESEARCH and PUBLIC HEALTH.2015,12(11):13662-13677.doi:10.3390/ijerph121113662.
APA：
Ruizhi Zheng,Min Yang,Yuqian Bao,Hong Li,Zhongyan Shan...&Maode Lai.(2015).Prevalence and Determinants of Metabolic Health in Subjects with Obesity in Chinese Population.INTERNATIONAL JOURNAL of ENVIRONMENTAL RESEARCH and PUBLIC HEALTH,12,(11)
MLA：
Ruizhi Zheng,et al."Prevalence and Determinants of Metabolic Health in Subjects with Obesity in Chinese Population".INTERNATIONAL JOURNAL of ENVIRONMENTAL RESEARCH and PUBLIC HEALTH 12..11(2015):13662-13677
