Strategically acquired gradient echo (STAGE)-derived MR angiography might be a superior alternative method to time-of-flight MR angiography in visualization of leptomeningeal collaterals
单位：[1]Department of Radiology, Tianjin First Central Hospital, 24 FukangRoad, Nankai District, Tianjin 300192, China[2]Department of Radiology, Beijing Friendship Hospital, CapitalMedical University, 95 Yong’an Road, Xicheng District,Beijing 100050, China医技科室影像中心放射科首都医科大学附属北京友谊医院[3]Department of Radiology, First Central Clinical College, TianjinMedical University, 22 Qixiangtai Road, Heping District,Tianjin 300070, China[4]Department of Neurology, Wayne State University School ofMedicine, 4201 St Antoine, Detroit, MI 48201, USA[5]Department of Radiology, Wayne State University School ofMedicine, 4201 St Antoine, Detroit, MI 48201, USA[6]Department of Neurosurgery, Tianjin First Central Hospital, 24Fukang Road, Nankai District, Tianjin 300192, China
Objectives This study aimed to compare the performance of strategically acquired gradient echo (STAGE)-derived MR angiography and time-of-flight MR angiography (TOF-MRA) in visualization of leptomeningeal collaterals (LMCs). Methods Between May 2018 and January 2020, 75 participants (47 healthy volunteers and 28 intracranial atherosclerotic disease [ICAD] patients) undergoing TOF-MRA and STAGE-MRA were prospectively included. Image quality was scored at the internal carotid artery (ICA) terminus, proximal middle cerebral artery (MCA), and LMCs. Quantitative analysis included calculation of contrast-to-noise ratios (CNRs) in the M1-4 segments and number of LMCs counted in the line signal intensity profiles. Comparisons of image qualitative scores, CNRs, and number of LMCs were calculated using the Wilcoxon rank-sum test. Results Image qualitative scores were significantly higher in STAGE-MRA than in TOF-MRA for the ICA terminus, proximal MCA, and LMCs (ps < 0.05) in 75 participants. When referred to digital subtraction angiography (DSA) in 25 ICAD patients, STAGE-MRA showed higher qualitative scores only at LMCs. CNRs in the M1-4 segments were significantly higher in STAGE-MRA than in TOF-MRA (218.7 +/- 90.7 vs 176.2 +/- 72.6, 195.7 +/- 86.0 vs 146.6 +/- 71.7, 176.4 +/- 71.6 vs 125.8 +/- 61.1, 126.2 +/- 62.9 vs 78.8 +/- 43.6; all ps < 0.001). STAGE-MRA showed more LMCs (11.4 +/- 3.4) than TOF-MRA (8.4 +/- 3.3) with p < 0.05. Conclusions STAGE-MRA might be superior to TOF-MRA in qualitative and quantitative assessment of LMCs in both healthy volunteers and ICAD patients; thus, it may serve as an alternative method in evaluating LMC.
基金：
National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81871342]
第一作者单位：[1]Department of Radiology, Tianjin First Central Hospital, 24 FukangRoad, Nankai District, Tianjin 300192, China[2]Department of Radiology, Beijing Friendship Hospital, CapitalMedical University, 95 Yong’an Road, Xicheng District,Beijing 100050, China
共同第一作者：
推荐引用方式(GB/T 7714)：
Tang Ruowei,Zhang Qingqing,Chen Yongsheng,et al.Strategically acquired gradient echo (STAGE)-derived MR angiography might be a superior alternative method to time-of-flight MR angiography in visualization of leptomeningeal collaterals[J].EUROPEAN RADIOLOGY.2020,30(9):5110-5119.doi:10.1007/s00330-020-06840-7.
APA：
Tang, Ruowei,Zhang, Qingqing,Chen, Yongsheng,Liu, Song,Haacke, Ewart Mark...&Xia, Shuang.(2020).Strategically acquired gradient echo (STAGE)-derived MR angiography might be a superior alternative method to time-of-flight MR angiography in visualization of leptomeningeal collaterals.EUROPEAN RADIOLOGY,30,(9)
MLA：
Tang, Ruowei,et al."Strategically acquired gradient echo (STAGE)-derived MR angiography might be a superior alternative method to time-of-flight MR angiography in visualization of leptomeningeal collaterals".EUROPEAN RADIOLOGY 30..9(2020):5110-5119
医学