单位：[1]Department of Orthopedics, China-Japan Friendship Hospital, China Japan Friendship Institute of Clinical Medicine, Chinese Academy of Medical Sciences, Peking Union Medical College, Graduate School of Peking Union Medical College, Beijing 100029, China[2]Department of Orthopedics, People's Hospital of Ningxia Hui Autonomous Region, Yinchuan, Ningxia Hui Autonomous Region 750001, China
Chondrocytes are the sole cellular constituents of normal cartilage. The degeneration and apoptosis of these cells are considered the main cause of osteoarthritis (OA). Previous studies have suggested that the enhancement of autophagy in chondrocytes can delay the progression of osteoarthritis by affecting intracellular metabolic activity, i.e., by regulating the metabolism of nutrients, which can delay cell aging and death. In this review, we explored the relationship between autophagy and chondrocyte metabolism and provided new ideas for the prevention and treatment of OA.
基金：
Fundamental Research Funds for the Central UniversitiesFundamental Research Funds for the Central Universities [3332018168]
语种：
外文
被引次数：
WOS：
中科院(CAS)分区：
出版当年[2018]版：
大类|3 区生物
小类|3 区生物工程与应用微生物4 区医学：研究与实验
最新[2025]版：
大类|4 区医学
小类|4 区生物工程与应用微生物4 区医学：研究与实验
JCR分区：
出版当年[2017]版：
Q2BIOTECHNOLOGY & APPLIED MICROBIOLOGYQ3MEDICINE, RESEARCH & EXPERIMENTAL
最新[2023]版：
Q3BIOTECHNOLOGY & APPLIED MICROBIOLOGYQ3MEDICINE, RESEARCH & EXPERIMENTAL
第一作者单位：[1]Department of Orthopedics, China-Japan Friendship Hospital, China Japan Friendship Institute of Clinical Medicine, Chinese Academy of Medical Sciences, Peking Union Medical College, Graduate School of Peking Union Medical College, Beijing 100029, China
共同第一作者：
通讯作者：
推荐引用方式(GB/T 7714)：
Luo Pan,Gao Fuqiang,Niu Dongsheng,et al.The Role of Autophagy in Chondrocyte Metabolism and Osteoarthritis: A Comprehensive Research Review[J].BIOMED RESEARCH INTERNATIONAL.2019,2019:doi:10.1155/2019/5171602.
APA：
Luo, Pan,Gao, Fuqiang,Niu, Dongsheng,Sun, Xichun,Song, Qiang...&Sun, Wei.(2019).The Role of Autophagy in Chondrocyte Metabolism and Osteoarthritis: A Comprehensive Research Review.BIOMED RESEARCH INTERNATIONAL,2019,
MLA：
Luo, Pan,et al."The Role of Autophagy in Chondrocyte Metabolism and Osteoarthritis: A Comprehensive Research Review".BIOMED RESEARCH INTERNATIONAL 2019.(2019)
