单位：[1]Peking University China-Japan Friendship School of clinical medicine, NO 2, East Yinghua Road, Chaoyang District, Beijing 100029, China[2]Department of Respiratory and Critical Care Medicine, Center of Respiratory Medicine, China-Japan Friendship Hospital, NO 2, East Yinghua Road, Chaoyang District, Beijing 100029, China[3]Institute of Respiratory Medicine, Chinese Academy of Medical Sciences, NO 2, East Yinghua Road, Chaoyang District, Beijing 100029, China[4]National Clinical Research Center for Respiratory Diseases, NO 2, East Yinghua Road, Chaoyang District, Beijing 100029, China[5]Chinese Academy of Medical Sciences ＆ Peking Union Medical College, No.1 Shuaifuyuan, Wangfujing, Dongcheng District, Beijing, 100730, China
Chronic thromboembolic pulmonary hypertension (CTEPH) is a serious condition characterized with chronic organized thrombi that obstruct the pulmonary vessels, leading to pulmonary hypertension (PH) and ultimately right heart failure. Although CTEPH is the only form of PH that can be cured with surgical intervention, not all patients with CTEPH will be deemed operable. Some CTEPH patients still have a poor prognosis. Therefore, the determination of diagnostic and prognostic biomarkers of CTEPH is of great importance for the early intervention to improve prognosis of patients with CTEPH. Several markers related to multiple mechanisms of CTEPH have been recently identified as circulating diagnostic and prognostic biomarkers in these patients. However, the existing literature review of biomarkers of CTEPH is relatively sparse. In this article, we review recent advances in circulating biomarkers of CTEPH and describe future applications of these biomarkers in the management of CTEPH.
基金：
National Key Research and Development Program of China [2016YFC0905600]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81570049]
语种：
外文
被引次数：
WOS：
中科院(CAS)分区：
出版当年[2018]版：
大类|3 区医学
小类|4 区心脏和心血管系统4 区呼吸系统
最新[2025]版：
大类|4 区医学
小类|4 区心脏和心血管系统4 区呼吸系统
JCR分区：
出版当年[2017]版：
Q2CARDIAC & CARDIOVASCULAR SYSTEMSQ3RESPIRATORY SYSTEM
最新[2023]版：
Q2CARDIAC & CARDIOVASCULAR SYSTEMSQ3RESPIRATORY SYSTEM
第一作者单位：[1]Peking University China-Japan Friendship School of clinical medicine, NO 2, East Yinghua Road, Chaoyang District, Beijing 100029, China[2]Department of Respiratory and Critical Care Medicine, Center of Respiratory Medicine, China-Japan Friendship Hospital, NO 2, East Yinghua Road, Chaoyang District, Beijing 100029, China[3]Institute of Respiratory Medicine, Chinese Academy of Medical Sciences, NO 2, East Yinghua Road, Chaoyang District, Beijing 100029, China[4]National Clinical Research Center for Respiratory Diseases, NO 2, East Yinghua Road, Chaoyang District, Beijing 100029, China
通讯作者：
通讯机构：[1]Peking University China-Japan Friendship School of clinical medicine, NO 2, East Yinghua Road, Chaoyang District, Beijing 100029, China[2]Department of Respiratory and Critical Care Medicine, Center of Respiratory Medicine, China-Japan Friendship Hospital, NO 2, East Yinghua Road, Chaoyang District, Beijing 100029, China[3]Institute of Respiratory Medicine, Chinese Academy of Medical Sciences, NO 2, East Yinghua Road, Chaoyang District, Beijing 100029, China[4]National Clinical Research Center for Respiratory Diseases, NO 2, East Yinghua Road, Chaoyang District, Beijing 100029, China[5]Chinese Academy of Medical Sciences ＆ Peking Union Medical College, No.1 Shuaifuyuan, Wangfujing, Dongcheng District, Beijing, 100730, China[*1]Chinese Academy of Medical Sciences ＆ Peking Union Medical College National Clinical Research Center for Respiratory Diseases Center of Respiratory Diseases, China-Japan Friendship Hospital, NO 2, East Yinghua Road, Chaoyang District, Beijing 100029, China[*2]National Clinical Research Center for Respiratory Diseases Center of Respiratory Diseases, China-Japan Friendship Hospital, NO 2, East Yinghua Road, Chaoyang District, Beijing 100029, China
