单位：[1]Department of Obstetrics and Gynecology, Beijing Friendship Hospital, Capital Medical University, Beijing, China临床科室妇产科妇产科首都医科大学附属北京友谊医院[2]Department of Obstetrics and Gynecology, Fuxing Hospital, Capital Medical University, Beijing, China
To evaluate the relationship between serum hormone or aquaporin-2 (AQP-2) and preeclampsia, patients with severe preeclampsia (A group), mild preeclampsia (B group), chronic hypertension (C group) and normal pregnant women (D group) were recruited and analysed. The AQP-2 level in placenta tissues was detected and the correlations of AQP-2 with serum hormone levels were analysed using linear correlation regression analysis. The differences of alpha foetal protein (AFP) and human chorionic gonadotropin (HCG) levels during mid-pregnancy, as well as the levels of AFP, HCG, unconjugated oestriol and progesterone during late pregnancy were significant among A, B, C and D groups (p < .05). The AQP-2 level in placenta tissues was higher in A group than that in other groups (p < .05). The AQP-2 was correlated with HCG (p < .05). In conclusion, AQP-2 may be involved in the development of severe preeclampsia, which may be related to serum HCG.
基金：
Beijing XiCheng District Health Bureau of Young Scientists (Science Nova) training projects
第一作者单位：[1]Department of Obstetrics and Gynecology, Beijing Friendship Hospital, Capital Medical University, Beijing, China
通讯作者：
通讯机构：[1]Department of Obstetrics and Gynecology, Beijing Friendship Hospital, Capital Medical University, Beijing, China[*1]Department of Obstetrics and Gynecology, Beijing Friendship Hospital, Capital Medical University, 95 Yong’an Road, Xicheng District, Beijing, 100050, China
推荐引用方式(GB/T 7714)：
Zhao Yurong,Lin Li,Lai Ailuan.Expression and significance of aquaporin-2 and serum hormones in placenta of patients with preeclampsia[J].JOURNAL of OBSTETRICS and GYNAECOLOGY.2018,38(1):42-48.doi:10.1080/01443615.2017.1327516.
APA：
Zhao, Yurong,Lin, Li&Lai, Ailuan.(2018).Expression and significance of aquaporin-2 and serum hormones in placenta of patients with preeclampsia.JOURNAL of OBSTETRICS and GYNAECOLOGY,38,(1)
MLA：
Zhao, Yurong,et al."Expression and significance of aquaporin-2 and serum hormones in placenta of patients with preeclampsia".JOURNAL of OBSTETRICS and GYNAECOLOGY 38..1(2018):42-48
