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Combined pharmacotherapy for osteonecrosis of the femoral head after severe acute respiratory syndrome and interstitial pneumonia: two and a half to fourteen year follow-up

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收录情况： ◇ SCIE

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单位： [1]Department of Orthopaedic Surgery, China-Japan Friendship Hospital, No. 2 Yinghua East Road, Chaoyang District, Beijing 100029, People’s Republic of China

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关键词： Osteonecrosis of the femoral head Porous media Subchondral plate Collapse Pharmacotherapy

摘要：

Purpose The purpose of this study was to retrospectively analyze the clinical, functional, and radiological outcomes of combined pharmacotherapy to ONFH after high-dose corticosteroid therapy. Method From August 2003 to June 2015, five patients (ten hips) of ONFH in ARCO stage I, after SARS and Interstitial pneumonia, were treated by combined pharmacotherapy. Lipo-prostaglandin E-1 10 mu g iv Bid x 28 days, enoxaparin 6000 iu H QD x 12 weeks, alendronate sodium tablet 10 mg QD x 1 year. The patients were fully weight-bearing following completion of the follow-up. Result For these five patients (ten hips), Harris score was 100 from the diagnosis to final follow-up time. Radiologic findings show no signs of collapse, necrotic focus was repaired, and ARCO stages were changed from I-C into IIB . Conclusion This combined pharmacotherapy has promising treatment results for delaying or preventing collapse of ONFH in ARCO stage I.

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出版当年[2017]版：

大类 | 3 区医学

小类 | 3 区骨科

最新[2025]版：

大类 | 3 区医学

小类 | 3 区骨科

JCR分区：

出版当年[2016]版：

Q1 ORTHOPEDICS

最新[2023]版：

Q2 ORTHOPEDICS

影响因子： 最新[2023版] 2 最新五年平均[2021-2025] 2.6 出版当年[2016版] 2.52 出版当年五年平均[2012-2016] 2.631 出版前一年[2015版] 2.387 出版后一年[2017版] 2.377

第一作者：

第一作者单位： [1]Department of Orthopaedic Surgery, China-Japan Friendship Hospital, No. 2 Yinghua East Road, Chaoyang District, Beijing 100029, People’s Republic of China

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