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Late onset MELAS with m.3243A > G mutation and its association with aneurysm formation

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单位: [1]Department of Neurology, First Affiliated Hospital of ChinaMedical University, No. 155 Nanjing North Street, Heping District, Shenyang, Liaoning 110001, China [2]The 96th Class, 7-Year Program, China Medical University, No.77 Puhe Road, Shenyang North New Area, Shenyang, Liaoning 110122, China [3]The 97th Class, 7-Year Program, China Medical University, No.77 Puhe Road, Shenyang North New Area, Shenyang, Liaoning 110122, China [4]Department of Cadre, The Central Hospital of Jiamusi City, No. 256 Zhongshan Road, Xiangyang District, Jiamusi, Heilongjiang 154002, China [5]Department of Neurology, Capital Medical University Affiliated Beijing Friendship Hospital, No. 95 Yongan Road, Xicheng District, Beijing 100050, China
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关键词: MELAS Aneurysm Nitric oxide synthase Apoptosis

摘要:
We reported a 53-year-old with late-onset mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS) accompanied by aneurysm and large vessel dilations. Most studies have focused on microangiopathy causing stroke-like episodes. We report a case to describe large vessel involvement in clinical considerations, and possible mechanisms of aneurysm formation. We recommended regular angiographic examination for patients with MELAS.

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出版当年[2016]版:
大类 | 3 区 医学
小类 | 4 区 内分泌学与代谢 4 区 神经科学
最新[2025]版:
大类 | 4 区 医学
小类 | 4 区 内分泌学与代谢 4 区 神经科学
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出版当年[2015]版:
Q3 ENDOCRINOLOGY & METABOLISM Q3 NEUROSCIENCES
最新[2023]版:
Q2 ENDOCRINOLOGY & METABOLISM Q2 NEUROSCIENCES

影响因子: 最新[2023版] 最新五年平均[2021-2025] 出版当年[2015版] 出版当年五年平均[2011-2015] 出版前一年[2014版] 出版后一年[2016版]

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第一作者单位: [1]Department of Neurology, First Affiliated Hospital of ChinaMedical University, No. 155 Nanjing North Street, Heping District, Shenyang, Liaoning 110001, China [2]The 96th Class, 7-Year Program, China Medical University, No.77 Puhe Road, Shenyang North New Area, Shenyang, Liaoning 110122, China
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