单位：[1]Graduate School, Beijing University of Chinese Medicine, Beijing 100029, China[2]Department of Neurology, China-Japan Friendship Hospital, Beijing 100029, China[3]Department of Neurology, Southwest Hospital, Third Military Medical University, Chongqing 400038, China[4]Department of Radiology, China-Japan Friendship Hospital, Beijing 100029, China
The aim of this study was to evaluate the safety and effectiveness of percutaneous transluminal angioplasty and stenting (PTAS) for intracranial atherosclerotic disease (ICAD) by conducting a meta-analysis. Two independent observers searched PubMed, EMBASE, and Cochrane Library for relevant studies up to 31 December 2016. A meta-analysis was conducted using Review Manager 5.3. Three studies involving 581 cases were included. The meta-analysis indicated that any stroke (RR = 3.13; 95% CI: 1.80-5.42), ischemic stroke (RR = 2.15; 95% CI: 1.19-3.89), and intracranial hemorrhage (RR = 14.71; 95% CI: 1.96-110.48) within 30 days in medical therapy alone were lower compared with PTAS plus medical therapy, but there were no significant differences in any stroke and ischemic stroke beyond 30 days between the two groups. There were also no significant differences in any death and myocardial infarction between the two groups. This meta-analysis demonstrated that, compared with medical therapy alone, PTAS for ICAD had a high risk of complication, but most complications in PTAS group occurred within 30 days after the operation, and beyond 30 days the PTAS was not inferior compared with medical therapy alone. Further studies are needed to reduce the periprocedural complications and reappraise the PTAS.
基金：
National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81173595, 81471194]; China-Japan Friendship Hospital Youth Science and Technology Excellence Project [2014-QNYC-A-04]; Clinical Innovation Foundation of Third Military Medical University [SWH2013LC18]
语种：
外文
被引次数：
WOS：
中科院(CAS)分区：
出版当年[2016]版：
大类|3 区生物
小类|3 区生物工程与应用微生物4 区医学：研究与实验
最新[2025]版：
大类|4 区医学
小类|4 区生物工程与应用微生物4 区医学：研究与实验
JCR分区：
出版当年[2015]版：
Q3BIOTECHNOLOGY & APPLIED MICROBIOLOGYQ3MEDICINE, RESEARCH & EXPERIMENTAL
最新[2023]版：
Q3BIOTECHNOLOGY & APPLIED MICROBIOLOGYQ3MEDICINE, RESEARCH & EXPERIMENTAL
第一作者单位：[1]Graduate School, Beijing University of Chinese Medicine, Beijing 100029, China[2]Department of Neurology, China-Japan Friendship Hospital, Beijing 100029, China
共同第一作者：
通讯作者：
推荐引用方式(GB/T 7714)：
Li ZhongHao,Zhou ZhenHua,Zhu XianJin,et al.Current Status and Future Perspective of Stenting for Symptomatic Intracranial Atherosclerotic Disease: A Meta-Analysis[J].BIOMED RESEARCH INTERNATIONAL.2017,2017:doi:10.1155/2017/3258681.
APA：
Li, ZhongHao,Zhou, ZhenHua,Zhu, XianJin,Liu, Wei,Chen, YaWen...&Liu, ZunJing.(2017).Current Status and Future Perspective of Stenting for Symptomatic Intracranial Atherosclerotic Disease: A Meta-Analysis.BIOMED RESEARCH INTERNATIONAL,2017,
MLA：
Li, ZhongHao,et al."Current Status and Future Perspective of Stenting for Symptomatic Intracranial Atherosclerotic Disease: A Meta-Analysis".BIOMED RESEARCH INTERNATIONAL 2017.(2017)
