Sulfur dioxide (SO2) is a toxic gas and air pollutant. The toxic effects of SO2 have been extensively studied. Oxidative damage due to SO2 can occur in multiple organs. Inhaled SO2 can also cause chromosomal aberrations, DNA damage and gene mutations in mammals. However, SO2 can also be generated from the sulfur-containing amino acid, Lcysteine. Recent studies have shown that SO2 has a vasorelaxant effect, and ameliorates pulmonary hypertension and vascular remodeling. SO2 can also reduce lung injury and myocardial injury in rats. In addition, SO2 reduces myocardial ischemia-reperfusion injury and atherosclerotic lesions. Therefore, SO2 exerts both detrimental and protective effects in mammals. Is SO2 a foe or friend for life?
基金：
National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81441009]
第一作者单位：[1]Capital Med Univ, Beijing Friendship Hosp, Dept Pediat, Yongan Str 95 West Dist, Beijing 100050, Peoples R China
通讯作者：
推荐引用方式(GB/T 7714)：
Wang Xin-Bao,Cui Hong,Liu Xiao-Hong,et al.Sulfur dioxide: foe or friend for life?[J].HISTOLOGY and HISTOPATHOLOGY.2017,32(12):1231-1238.doi:10.14670/HH-11-904.
APA：
Wang, Xin-Bao,Cui, Hong,Liu, Xiao-Hong&Du, Jun-Bao.(2017).Sulfur dioxide: foe or friend for life?.HISTOLOGY and HISTOPATHOLOGY,32,(12)
MLA：
Wang, Xin-Bao,et al."Sulfur dioxide: foe or friend for life?".HISTOLOGY and HISTOPATHOLOGY 32..12(2017):1231-1238
