The objective of this study was to explore the value of ultrasound-guided percutaneous microwave thermoablation to treat secondary hyperparathyroidism (SHPT). One hundred and thirty-eight parathyroid glands from 56 patients with SHPT were ablated in this study. All the parathyroid glands were evaluated by real-time contrast-enhanced ultrasound before, during and after ablation. Changes in serum parathyroid hormone (sPTH) levels were measured before treatment and at 1 h, 1 wk, 1 mo and 6 mo after thermoablation treatment. All 56 cases had a 1-mo follow-up, and 34 cases had a 6-mo follow-up. The sPTH level of the 54 cases 1 mo after ablation was significantly lower than that before (p < 0.05). In the 34 cases that had a 6-mo follow-up, the sPTH levels were also significantly lower at 6 mo after ablation than before (p < 0.05). Bone pain in patients improved post-operatively (p, 0.05), but itchiness and insomnia did not improve (p. 0.05). Ultrasound-guided percutaneous microwave thermoablation is a feasible and effective non-surgical alternative treatment for SHPT patients. (C) 2016 Published by Elsevier Inc. on behalf of World Federation for Ultrasound in Medicine & Biology.
基金:
Capital characteristic clinical application research [Z131107002213143]
语种:
外文
被引次数:
WOS:
PubmedID:
中科院(CAS)分区:
出版当年[2015]版:
大类|3 区医学
小类|2 区声学3 区核医学
最新[2025]版:
大类|3 区医学
小类|3 区声学3 区核医学
JCR分区:
出版当年[2014]版:
Q1ACOUSTICSQ2RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
最新[2023]版:
Q2ACOUSTICSQ2RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
第一作者单位:[1]Department of Ultrasound, Beijing Friendship Hospital Affiliated to Capital Medical University, Beijing, China
通讯作者:
通讯机构:[1]Department of Ultrasound, Beijing Friendship Hospital Affiliated to Capital Medical University, Beijing, China[*1]Department of Ultrasound, Beijing Friendship Hospital Affiliated to Capital Medical University, Beijing 100050, China.
推荐引用方式(GB/T 7714):
Zhao Junfeng,Qian Linxue,Zu Yuan,et al.EFFICACY OF ABLATION THERAPY FOR SECONDARY HYPERPARATHYROIDISM BY ULTRASOUND GUIDED PERCUTANEOUS THERMOABLATION[J].ULTRASOUND in MEDICINE and BIOLOGY.2016,42(5):1058-1065.doi:10.1016/j.ultrasmedbio.2015.08.021.
APA:
Zhao, Junfeng,Qian, Linxue,Zu, Yuan,Wei, Ying&Hu, Xiangdong.(2016).EFFICACY OF ABLATION THERAPY FOR SECONDARY HYPERPARATHYROIDISM BY ULTRASOUND GUIDED PERCUTANEOUS THERMOABLATION.ULTRASOUND in MEDICINE and BIOLOGY,42,(5)
MLA:
Zhao, Junfeng,et al."EFFICACY OF ABLATION THERAPY FOR SECONDARY HYPERPARATHYROIDISM BY ULTRASOUND GUIDED PERCUTANEOUS THERMOABLATION".ULTRASOUND in MEDICINE and BIOLOGY 42..5(2016):1058-1065