单位：[1]Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, China[2]Center for Biomedical Imaging Research, Tsinghua University, Beijing, China[3]Department of Ultrasound, Beijing Friendship Hospital, Capital Medical University, Beijing, China医技科室影像中心超声医学科首都医科大学附属北京友谊医院
Pulse wave velocity (PWV), a measurement of arterial stiffness, can be estimated locally by determining the time delay of the pulse waveforms for a known distance as measured in an ultrasound image. Our aim was to compare three ultrasound-based methods for estimation of local PWV based on the measurement of diameter distension waveforms, displacement waveforms of the anterior wall and displacement waveforms of the posterior wall, respectively, in human common carotid arteries in vivo. The local PWVs at both systolic foot (PWVsf) and dicrotic notch (PWVdn) were estimated from ultrasound radiofrequency data of 25 healthy and 24 hypertensive patients for each method. PWV estimation using the distension waveform method was found to have the highest precision in both groups. Both PWVsf and PWVdn were significantly higher in the hypertensive group compared with the healthy group using the distension waveform method (PWVsf: 6.08 +/- 1.70 m/s vs. 4.75 +/- 0.92 m/s, p = 0.000014; PWVdn: 7.83 +/- 2.26 m/s vs. 5.21 +/- 0.95 m/s, p < 0.000001), whereas there was no significant difference at a significance level of 0.01 between the two groups when the anterior or posterior wall waveform method was used. Thus, the difference in arterial stiffness between the two groups could be discriminated well by the distension waveform method. The local PWV estimated using distension waveforms might be a promising index for arterial stiffness characterization and hypertension management. (C) 2016 World Federation for Ultrasound in Medicine & Biology.
基金：
National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [61271131, 61322101, 81471665, 81561168023, 81541132]; Tsinghua University Initiative Scientific Research Program
语种：
外文
被引次数：
WOS：
PubmedID：
中科院(CAS)分区：
出版当年[2015]版：
大类|3 区医学
小类|2 区声学3 区核医学
最新[2025]版：
大类|3 区医学
小类|3 区声学3 区核医学
JCR分区：
出版当年[2014]版：
Q1ACOUSTICSQ2RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
最新[2023]版：
Q2ACOUSTICSQ2RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
第一作者单位：[1]Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, China[2]Center for Biomedical Imaging Research, Tsinghua University, Beijing, China
通讯作者：
通讯机构：[1]Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, China[2]Center for Biomedical Imaging Research, Tsinghua University, Beijing, China[*1]Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing 100084, China
推荐引用方式(GB/T 7714)：
Huang Chengwu,Su Yuan,Zhang Hong,et al.COMPARISON OF DIFFERENT PULSE WAVEFORMS FOR LOCAL PULSE WAVE VELOCITY MEASUREMENT IN HEALTHYAND HYPERTENSIVE COMMON CAROTID ARTERIES IN VIVO[J].ULTRASOUND in MEDICINE and BIOLOGY.2016,42(5):1111-1123.doi:10.1016/j.ultrasmedbio.2015.12.021.
APA：
Huang, Chengwu,Su, Yuan,Zhang, Hong,Qian, Lin-Xue&Luo, Jianwen.(2016).COMPARISON OF DIFFERENT PULSE WAVEFORMS FOR LOCAL PULSE WAVE VELOCITY MEASUREMENT IN HEALTHYAND HYPERTENSIVE COMMON CAROTID ARTERIES IN VIVO.ULTRASOUND in MEDICINE and BIOLOGY,42,(5)
MLA：
Huang, Chengwu,et al."COMPARISON OF DIFFERENT PULSE WAVEFORMS FOR LOCAL PULSE WAVE VELOCITY MEASUREMENT IN HEALTHYAND HYPERTENSIVE COMMON CAROTID ARTERIES IN VIVO".ULTRASOUND in MEDICINE and BIOLOGY 42..5(2016):1111-1123
