单位：[1]Department of Epidemiology, Capital Medical University, Beijing Anzhen Hospital, Beijing Institute of Heart, Lung and Blood Vessel Disease, China首都医科大学附属安贞医院[2]Hematology Department, Capital Medical University, Friendship Hospital, China临床科室血液科血液科首都医科大学附属北京友谊医院[3]Department of Internal Medicine, Baton Rouge General Medical Center, Baton Rouge, LA, USA[4]Department of Epidemiology, School of Public Health, Brown University, Providence, RI, USA[5]Cardiology Department, Capital Medical University, Beijing Anzhen Hospital, China首都医科大学附属安贞医院
The optimal treatment for in-stent restenosis (ISR) of both bare-metal stent (BMS) and drug-eluting stent (DES) is currently unclear. The aim of this meta-analysis was to assess the role of drug-eluting balloon (DEB) as an optional treatment for ISR. We searched PubMed, MEDLINE, EMBASE, BIOS, and Web of Science from 2005 to July 2014. Eight studies, enrolling 1413 patients were included. Main end points were late lumen loss (LLL), binary in-segment restenosis (BR), major adverse cardiac events (MACEs), target lesion revascularization (TLR), death, myocardial infarction (MI), and stent thrombosis (ST). When compared to plain old balloon angioplasty (POBA), DEB treatment significantly reduced the risk of MACE (risk rato [RR] 0.37, P < .01), death (RR 0.44, P = .04), TLR (RR 0.27, P < .01), BR (RR [95% CI]: 0.23[0.12 to 0.43], P < .01) and associated with better outcomes of LLL ( 0.50 [ 0.65 to 0.35] mm, P < .01). However, the differences were not significant between DEB treatment and DES treatment in all primary and secondary end points. The DEB was a better option to treat ISR when compared to POBA. However, it had similar effects as DES.
第一作者单位：[1]Department of Epidemiology, Capital Medical University, Beijing Anzhen Hospital, Beijing Institute of Heart, Lung and Blood Vessel Disease, China
通讯作者：
通讯机构：[5]Cardiology Department, Capital Medical University, Beijing Anzhen Hospital, China[*1]Department Capital Medical University, Beijing Anzhen Hospital, Beijing 100021, China.
推荐引用方式(GB/T 7714)：
Gao Shen,Shen Jing,Mukku Venkata Kishore,et al.Efficacy of Drug-Eluting Balloons for Patients With In-Stent Restenosis: A Meta-Analysis of 8 Randomized Controlled Trials[J].ANGIOLOGY.2016,67(7):612-621.doi:10.1177/0003319715611826.
APA：
Gao, Shen,Shen, Jing,Mukku, Venkata Kishore,Wang, Mei Jia,Akhtar, Muzina&Liu, Wei.(2016).Efficacy of Drug-Eluting Balloons for Patients With In-Stent Restenosis: A Meta-Analysis of 8 Randomized Controlled Trials.ANGIOLOGY,67,(7)
MLA：
Gao, Shen,et al."Efficacy of Drug-Eluting Balloons for Patients With In-Stent Restenosis: A Meta-Analysis of 8 Randomized Controlled Trials".ANGIOLOGY 67..7(2016):612-621
