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Immunoglobulin G4-Related Disease in the Skull Base Mimicking Nasopharyngeal Carcinoma

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收录情况: ◇ SCIE

单位: [1]China Japan Friendship Hosp, Dept Otolaryngol, Beijing 100029, Peoples R China [2]China Japan Friendship Hosp, Dept Pathol, Beijing 100029, Peoples R China [3]China Japan Friendship Hosp, Dept Radiol, Beijing 100029, Peoples R China
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关键词: Immunoglobulin G4-related disease skull base nasopharyngeal malignance

摘要:
Immunoglobulin G4-related disease (IgG4-RD) is a rare clinical condition. Although it has been described in the head and neck region, skull base involvement is exceedingly uncommon. We present a clinical report of a patient with IgG4-RD of the skull base that mimicked nasopharyngeal cancer. This case highlights challenges in the clinical diagnosis of this rare condition. The diagnosis could be made only on histopathologic evaluation, which showed dense fibrosis with lymphoplasmacytic infiltration by IgG4-positive plasma cells. Serum IgG4 level was also elevated. Once IgG4-RD was confirmed, treatment with glucocorticoid yielded a good clinical outcome.

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出版当年[2014]版:
大类 | 4 区 医学
小类 | 4 区 外科
最新[2025]版:
大类 | 4 区 医学
小类 | 4 区 外科
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出版当年[2013]版:
Q4 SURGERY
最新[2023]版:
Q3 SURGERY

影响因子: 最新[2023版] 最新五年平均[2021-2025] 出版当年[2013版] 出版当年五年平均[2009-2013] 出版前一年[2012版] 出版后一年[2014版]

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第一作者单位: [1]China Japan Friendship Hosp, Dept Otolaryngol, Beijing 100029, Peoples R China
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通讯机构: [1]China Japan Friendship Hosp, Dept Otolaryngol, Beijing 100029, Peoples R China [*1]China Japan Friendship Hosp, Dept Otolaryngol, 2 Yinghuadong St, Beijing 100029, Peoples R China
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