单位：[1]Chinese Peoples Liberat Army Gen Hosp, Dept Intervent Ultrasound, Beijing 100853, Peoples R China[2]Capital Med Univ, Beijing Friendship Hosp, Dept Ultrasound, Beijing, Peoples R China首都医科大学附属北京友谊医院
A total of 142 premenopausal women with symptomatic adenomyosis underwent ultrasound (US)guided percutaneous microwave ablation (PMWA) at the Chinese PLA General Hospital. This study aimed to evaluate changes in serum pituitary, gonadal hormone and cancer antigen 125 (CA125) levels after US-guided PMWA. Therefore, estradiol (E-2), follicle-stimulating hormone (FSH), prolactin (PRL) and CA125 levels were evaluated before ablation and at 3, 6, 9 and 12 months after ablation. No significant differences were observed in the E-2 and FSH levels pre-ablation and during follow-up (E-2: p = 0.933, p = 0.987, p = 0.106, p = 0.936; FSH: p = 0.552, p = 0.295, p = 0.414, p = 0.760). The mean absolute values of serum CA125 and PRL were significantly decreased at 3, 6, 9 and 12 months after ablation (CA125: p < 0.001, p < 0.001, p < 0.001, p = 0.003; PRL: p < 0.001, p < 0.001, p < 0.001, p < 0.001). A significant correlation between changes in CA125 levels and uterine volume was found (p < 0.001). No evidence of a decline in ovarian function was observed after US-guided PMWA.
基金：
National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81371562]; Clinical Application Research of Capital Characteristic [Z131107002213144]
第一作者单位：[1]Chinese Peoples Liberat Army Gen Hosp, Dept Intervent Ultrasound, Beijing 100853, Peoples R China[2]Capital Med Univ, Beijing Friendship Hosp, Dept Ultrasound, Beijing, Peoples R China
通讯作者：
推荐引用方式(GB/T 7714)：
Yang Yu,Zhang Jing,Han Zhi-yu,et al.Ultrasound-guided percutaneous microwave ablation for adenomyosis: efficacy of treatment and effect on ovarian function[J].SCIENTIFIC REPORTS.2015,5:doi:10.1038/srep10034.
APA：
Yang Yu,Zhang Jing,Han Zhi-yu,Ma Xia,Hao Yan-li...&Zhang Bing-song.(2015).Ultrasound-guided percutaneous microwave ablation for adenomyosis: efficacy of treatment and effect on ovarian function.SCIENTIFIC REPORTS,5,
MLA：
Yang Yu,et al."Ultrasound-guided percutaneous microwave ablation for adenomyosis: efficacy of treatment and effect on ovarian function".SCIENTIFIC REPORTS 5.(2015)
