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The Development of Biomimetic Spherical Hydroxyapatite/Polyamide 66 Biocomposites as Bone Repair Materials

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单位: [1]Chinese Peoples Liberat Army Gen Hosp, Dept Orthopaed, Beijing 100853, Peoples R China [2]China Japan Friendship Hosp, Dept Endocrinol, Beijing 100029, Peoples R China
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A novel biomedical material composed of spherical hydroxyapatite (s-IIA) and polyamide 66 (PA) biocomposite (s-IIA/PA) was prepared, and its composition, mechanical properties, and cytocompatibility were characterized and evaluated. The results showed that HA distributed uniformly in the s-HA/PA matrix. Strong molecule interactions and chemical bonds were presented between the s-HA and PA in the composites confirmed by IR and XRD. The composite had excellent compressive strength in the range between 95 and 132 MPa, close to that of natural bone. In vitro experiments showed the s-HA/PA composite could improve cell growth, proliferation, and differentiation. Therefore, the developed s-HA/PA composites in this study might be used for tissue engineering and bone repair.

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出版当年[2013]版:
大类 | 4 区 工程技术
小类 | 4 区 高分子科学
最新[2025]版:
大类 | 3 区 化学
小类 | 3 区 高分子科学
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出版当年[2012]版:
Q3 POLYMER SCIENCE
最新[2023]版:
Q2 POLYMER SCIENCE

影响因子: 最新[2023版] 最新五年平均[2021-2025] 出版当年[2012版] 出版当年五年平均[2008-2012] 出版前一年[2011版] 出版后一年[2013版]

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第一作者单位: [1]Chinese Peoples Liberat Army Gen Hosp, Dept Orthopaed, Beijing 100853, Peoples R China
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