单位：[1]Department of Endocrinology, People’s Hospital of Peking University, Beijing, China,[2]Department of Epidemiology and Biostatistics, School of Public Health, Tianjin Medical University, Tianjin, China,[3]Department of Endocrinology, The General Hospital of Beijing Military Command, Beijing, China,[4]Department of Endocrinology, First Hospital of Peking University, Beijing, China,[5]Department of Endocrinology, Sino-Japan Friendship Hospital, Beijing, China,[6]Department of Endocrinology, Shanghai Sixth People’s Hospital, Shanghai Jiaotong University, Shanghai, China,[7]Department of Endocrinology, Changhai Hospital of Shanghai, Shanghai, China,[8]Department of Endocrinology, The Second Xiangya Hospital of Central South University, Changsha, China,[9]Department of Endocrinology, Xijing Hospital Affiliated to 4th Military Medical University, Xi’an, China,[10]Department of Endocrinology, Nanjing Drum Tower Hospital, Nanjing, Jiansu, China,[11]Department of Endocrinology, Hospital of Guiyang Medical University, Guiyang, China,[12]Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China中山大学附属第三医院
Objective: To investigate the association of hyperglycemia with blood pressure control goal in the patients with type 2 diabetes (T2D) cared by tertiary hospitals in China. Study Design and Methods: A cross sectional survey of 29442 patients was conducted in 77 tertiary hospitals in 4 major cities in China in 2011 and 18350 of them without known hypertension were used in the analysis. Univariable and multivariable logistic regression analysis stratified on cities and hospitals was performed to obtain odds ratio of factors of interest for achievement of the blood pressure treatment goal, i.e., 140/80 mmHg as recommended by American Diabetes Association (ADA). Sensitivity analysis was performed after re-inclusion of 11902 patients with diagnosed hypertension. Findings from were further replicated in patients with T2D recruited using the same protocol from tertiary hospitals located in other central cities in China. Results: The mean age was 58.2 (SD: 11.3) years and 53.3% were male, with a median of 4 years of disease duration. A total of 12129 patients (58.2%) did not achieve the ADA recommended goal for BP control. After adjusting for covariables, hyperglycemia was associated with failure to achieve the BP goal (OR of HbA1c at 6.5%-6.9% vs. <6.0%: 1.22, 95%CI: 1.08 to 1.39; OR of 7.0%-7.0% vs. <6.0%: 1.37, 1.21 to 1.54 and OR of >= 8.0% vs. <6.0%: 1.22, 95%CI: 1.08 to 1.38). The sensitivity analysis and the replication analysis showed similar results. Conclusions: Hyperglycemia defined as HbA1c >= 6.5% increased the risk of failure to achieve the BP goal in T2D patients.
第一作者单位：[1]Department of Endocrinology, People’s Hospital of Peking University, Beijing, China,
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推荐引用方式(GB/T 7714)：
Linong Ji,Xinyue Zhi,Juming Lu,et al.Hyperglycemia and Blood Pressure Treatment Goal: A Cross Sectional Survey of 18350 Patients with Type 2 Diabetes in 77 Tertiary Hospitals in China[J].PLOS ONE.2014,9(8):doi:10.1371/journal.pone.0103507.
APA：
Linong Ji,Xinyue Zhi,Juming Lu,Xiaohui Guo,Wenying Yang...&Jianping Weng.(2014).Hyperglycemia and Blood Pressure Treatment Goal: A Cross Sectional Survey of 18350 Patients with Type 2 Diabetes in 77 Tertiary Hospitals in China.PLOS ONE,9,(8)
MLA：
Linong Ji,et al."Hyperglycemia and Blood Pressure Treatment Goal: A Cross Sectional Survey of 18350 Patients with Type 2 Diabetes in 77 Tertiary Hospitals in China".PLOS ONE 9..8(2014)
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