With the improvement of perinatal care and neonatal intensive care technology in recent years, a preterm infant, especially with small gestational age and very low birth weight, survives more and more. At the same time, adverse neurodevelopmental prognosis caused by brain damage in preterm infant also increased significantly. Preterm infant brain injury has become the most important factor for early death and neurodevelopment of preterm infant. Amplitude integration electroencephalogram (aEEG) has an important clinical value in the assessment of brain development in the maturity of preterm infant. With the application of a neonatal brain function monitor, we value the aEEG graphic continuity, periodicity, narrowband lower margin amplitude, and bandwidth score and analyze wide- and narrowband on the lower bounds of voltage and bandwidth. The graphics of preterm infant aEEG become mature with the growth of the gestational age (1). With the growth of corrected gestational age, the aEEG graphics of preterm infant has the following feature: lower bound voltage of narrowband rising and width narrowing of narrowband (2). Extrauterine life can speed up the maturation of aEEG graphics (3). The aEEG technology is a noninvasive, operable, and simple analysis and suitable for application in the newborn intensive care unit.