资源类型：
期刊
收录情况：
◇ SCIE
◇ 自然指数
文章类型：
论著
作者：
Li, Jianfeng[1,2]
*
;
Zhou, Lu[1,3]
;
Ye, Deyong[1,3]
;
Huang, Shixian[1,2]
;
Shao, Kun[1,2]
;
Huang, Rongqin[1,2]
;
Han, Liang[1,2]
;
Liu, Yang[1,2]
;
Liu, Shuhuan[1,2]
;
Ye, Liya[4]
;
Lou, Jinning[4]
;
Jiang, Chen[1,2,*1]
;
单位：
[1]Fudan Univ, Sch Pharm, Minist Educ, Key Lab Smart Drug Delivery, Shanghai 201203, Peoples R China
[2]Fudan Univ, Sch Pharm, PLA Dept Pharmaceut, Shanghai 201203, Peoples R China
[3]Fudan Univ, Sch Pharm, PLA Dept Med Chem, Shanghai 201203, Peoples R China
[4]Minist Hlth, China Japan Friendship Hosp, Inst Clin Med Sci, Beijing, Peoples R China
ISSN：
0935-9648
摘要：
The choline transporter (ChT) is used to transport choline-derivate-modified nanoparticles across the blood-brain barrier. It is demonstrated that ChT is an ideal Trojan horse. The choline-derivate-modified nanoparticles exhibit higher permeability across the brain capillary endothelial cells (BCECs) monolayer in vitro and higher gene distribution and expression in vivo.
基金：
National Basic Research Program of China (973program)National Basic Research Program of China [2007CB935802]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [30973652, 81172993]; Key new drug creation program [2009ZX09310-006]
被引次数：
60
WOS：
WOS:000297008100006
中科院(CAS)分区：
出版当年[2010]版：
大类
|
1 区
工程技术
小类
|
1 区
物理化学
1 区
材料科学：综合
1 区
物理：应用
2 区
化学综合
2 区
纳米科技
2 区
物理：凝聚态物理
最新[2025]版：
大类
|
1 区
材料科学
小类
|
1 区
化学：综合
1 区
材料科学：综合
1 区
纳米科技
1 区
物理：应用
1 区
物理：凝聚态物理
JCR分区：
出版当年[2009]版：
Q1
MATERIALS SCIENCE, MULTIDISCIPLINARY
Q1
PHYSICS, CONDENSED MATTER
Q1
NANOSCIENCE & NANOTECHNOLOGY
Q1
CHEMISTRY, PHYSICAL
Q1
PHYSICS, APPLIED
Q1
CHEMISTRY, MULTIDISCIPLINARY
最新[2023]版：
Q1
CHEMISTRY, MULTIDISCIPLINARY
Q1
CHEMISTRY, PHYSICAL
Q1
MATERIALS SCIENCE, MULTIDISCIPLINARY
Q1
NANOSCIENCE & NANOTECHNOLOGY
Q1
PHYSICS, APPLIED
Q1
PHYSICS, CONDENSED MATTER
影响因子：
最新[2023版] 27.4
最新五年平均[2021-2025] 30.2
出版当年[2009版] 8.379
出版当年五年平均[2005-2009] 9.836
出版前一年[2008版] 8.191
出版后一年[2010版] 10.88
第一作者：
Li, Jianfeng
第一作者单位：
[1]Fudan Univ, Sch Pharm, Minist Educ, Key Lab Smart Drug Delivery, Shanghai 201203, Peoples R China
[2]Fudan Univ, Sch Pharm, PLA Dept Pharmaceut, Shanghai 201203, Peoples R China
通讯作者：
Jiang, Chen
通讯机构：
[1]Fudan Univ, Sch Pharm, Minist Educ, Key Lab Smart Drug Delivery, Shanghai 201203, Peoples R China
[2]Fudan Univ, Sch Pharm, PLA Dept Pharmaceut, Shanghai 201203, Peoples R China
[*1]Fudan Univ, Sch Pharm, Minist Educ, Key Lab Smart Drug Delivery, 826 Zhangheng Rd, Shanghai 201203, Peoples R China
推荐引用方式(GB/T 7714)：
Li Jianfeng,Zhou Lu,Ye Deyong,et al.Choline-Derivate-Modified Nanoparticles for Brain-Targeting Gene Delivery[J].ADVANCED MATERIALS.2011,23(39):4516-+.doi:10.1002/adma.201101899.
APA：
Li, Jianfeng,Zhou, Lu,Ye, Deyong,Huang, Shixian,Shao, Kun...&Jiang, Chen.(2011).Choline-Derivate-Modified Nanoparticles for Brain-Targeting Gene Delivery.ADVANCED MATERIALS,23,(39)
MLA：
Li, Jianfeng,et al."Choline-Derivate-Modified Nanoparticles for Brain-Targeting Gene Delivery".ADVANCED MATERIALS 23..39(2011):4516-+
工程技术