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Association Between Urothelial Carcinoma After Renal Transplantation and Infection by Human Papillomavirus Types 16 and 18

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单位: [1]Capital Med Univ, Beijing Friendship Hosp, Dept Urol, Beijing, Peoples R China
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摘要:
Objective. To explore the association between urothelial carcinoma following renal transplantation and infection by human papillomavirus (HPV) types 16 and 18. Materials and Methods. Of 3780 patients who underwent renal transplantation, we identified 90 cases of urothelial carcinoma. Tumor tissues collected from the 90 renal transplant recipients were compared with those from 30 nontransplanted patients with bladder cancer (control group) for HPV types 16 and 18 using polymerase chain reactions. Results. Seven transplanted patients were HPV positive: HPV-16 was detected in 3 patients with bladder cancer (3/90; 3.3%), and HPV-18 in 2 patients with bilateral pelvic ureteral carcinoma (2/90; 2.2%), and 2 patients with bladder cancer (2/90; 2.2%). Only 2 cases from the control group were HPV positive (both HPV-18; 2/30; 5%). The difference between the RTR and control groups was not significant (P > .05). Conclusion. Malignant tumors in the urinary system following renal transplantation did not seems to be associated with infection by HPV-16 or -18.

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出版当年[2010]版:
大类 | 4 区 医学
小类 | 4 区 免疫学 4 区 外科 4 区 移植
最新[2025]版:
大类 | 4 区 医学
小类 | 4 区 免疫学 4 区 外科 4 区 移植
JCR分区:
出版当年[2009]版:
Q3 SURGERY Q4 TRANSPLANTATION Q4 IMMUNOLOGY
最新[2023]版:
Q4 IMMUNOLOGY Q4 SURGERY Q4 TRANSPLANTATION

影响因子: 最新[2023版] 最新五年平均[2021-2025] 出版当年[2009版] 出版当年五年平均[2005-2009] 出版前一年[2008版] 出版后一年[2010版]

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第一作者单位: [1]Capital Med Univ, Beijing Friendship Hosp, Dept Urol, Beijing, Peoples R China
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通讯机构: [1]Capital Med Univ, Beijing Friendship Hosp, Dept Urol, Beijing, Peoples R China [*1]Capital Med Univ, Beijing Friendship Hosp, Dept Urol, 95 YongAn Rd, Beijing, Peoples R China
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