Objective. To explore the association between urothelial carcinoma following renal transplantation and infection by human papillomavirus (HPV) types 16 and 18. Materials and Methods. Of 3780 patients who underwent renal transplantation, we identified 90 cases of urothelial carcinoma. Tumor tissues collected from the 90 renal transplant recipients were compared with those from 30 nontransplanted patients with bladder cancer (control group) for HPV types 16 and 18 using polymerase chain reactions. Results. Seven transplanted patients were HPV positive: HPV-16 was detected in 3 patients with bladder cancer (3/90; 3.3%), and HPV-18 in 2 patients with bilateral pelvic ureteral carcinoma (2/90; 2.2%), and 2 patients with bladder cancer (2/90; 2.2%). Only 2 cases from the control group were HPV positive (both HPV-18; 2/30; 5%). The difference between the RTR and control groups was not significant (P > .05). Conclusion. Malignant tumors in the urinary system following renal transplantation did not seems to be associated with infection by HPV-16 or -18.
第一作者单位:[1]Capital Med Univ, Beijing Friendship Hosp, Dept Urol, Beijing, Peoples R China
通讯作者:
通讯机构:[1]Capital Med Univ, Beijing Friendship Hosp, Dept Urol, Beijing, Peoples R China[*1]Capital Med Univ, Beijing Friendship Hosp, Dept Urol, 95 YongAn Rd, Beijing, Peoples R China
推荐引用方式(GB/T 7714):
Xiao J.,Zhu X.,Hao G. Y.,et al.Association Between Urothelial Carcinoma After Renal Transplantation and Infection by Human Papillomavirus Types 16 and 18[J].TRANSPLANTATION PROCEEDINGS.2011,43(5):1638-1640.doi:10.1016/j.transproceed.2011.03.053.
APA:
Xiao, J.,Zhu, X.,Hao, G. Y.,Zhu, Y. C.,Ma, L. L....&Tian, Y..(2011).Association Between Urothelial Carcinoma After Renal Transplantation and Infection by Human Papillomavirus Types 16 and 18.TRANSPLANTATION PROCEEDINGS,43,(5)
MLA:
Xiao, J.,et al."Association Between Urothelial Carcinoma After Renal Transplantation and Infection by Human Papillomavirus Types 16 and 18".TRANSPLANTATION PROCEEDINGS 43..5(2011):1638-1640