Objective To study the circulation, distribution, and genomic diversity of HPVs in common warts in Beijing area of China. Methods Forty eight patients with pathologically diagnosed common warts were screened for the presence of HPV with HPV type-specific PCR and direct sequencing analysis. The genomic diversity of HPVs prevalent in Chinese patients was analyzed based on LCR. Results Forty one (85.5%) samples were positive for HPV DNA, 13(31.7%)-HPV-57, 12(29.3%)-HPV-1a, 7(17%)-HPV-27 and 5(12.2%)-HPV-2a. Four cases were infected with two different HPV types, two (4.9%) with HPV-1a and HPV-27, one (2.4%) with HPV-1 and HPV-57 and one (2.4%) with HPV-27 and HPV-57. In contrast to the prevalence of single strain of novel HPV-57 variant and HPV-1 prototype, two HPV-2 and three HPV-27 novel variants were found to circulate in Beijing. Conclusion HPV-1, -2, -27 and -57 are predominantly prevalent in patients with common warts in Beijing.
语种：
外文
被引次数：
WOS：
中科院(CAS)分区：
出版当年[2008]版：
大类|4 区环境科学与生态学
小类|4 区环境科学4 区公共卫生、环境卫生与职业卫生
最新[2025]版：
大类|4 区医学
小类|4 区环境科学4 区公共卫生、环境卫生与职业卫生
JCR分区：
出版当年[2007]版：
Q4ENVIRONMENTAL SCIENCESQ4PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
第一作者单位：[1]Chinese Ctr Dis Control & Prevent, Natl Inst Viral Dis Control & Prevent, State Key Lab Infect Dis Prevent & Control, Beijing 100052, Peoples R China[2]Xi An Jiao Tong Univ, Sch Med, Xian 710061, Peoples R China
通讯作者：
推荐引用方式(GB/T 7714)：
Lei Yan-Jun,Gao Chen,Wang Chen,et al.Molecular Epidemiological Study on Prevalence of Human Papillomaviruses in Patients with Common Warts in Beijing Area[J].BIOMEDICAL and ENVIRONMENTAL SCIENCES.2009,22(1):55-61.doi:10.1016/S0895-3988(09)60023-4.
APA：
Lei, Yan-Jun,Gao, Chen,Wang, Chen,Han, Jun,Chen, Jian-Ming...&Dong, Xiao-Ping.(2009).Molecular Epidemiological Study on Prevalence of Human Papillomaviruses in Patients with Common Warts in Beijing Area.BIOMEDICAL and ENVIRONMENTAL SCIENCES,22,(1)
MLA：
Lei, Yan-Jun,et al."Molecular Epidemiological Study on Prevalence of Human Papillomaviruses in Patients with Common Warts in Beijing Area".BIOMEDICAL and ENVIRONMENTAL SCIENCES 22..1(2009):55-61
