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Coercivity dependence of inductive heat property of Fe3O4 nanoparticles in alternating current magnetic field

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单位: [1]Beijing Univ Chem Technol, State Key Lab Chem Resource Engn, Beijing 100029, Peoples R China [2]China Japan Friendship Hosp, Inst Med Clin Sci, Beijing 100029, Peoples R China [3]Tsinghua Univ, Sch Med, Beijing 100084, Peoples R China
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关键词: magnetite nanoparticles local hyperthermia cancer treatment biomedical applications

摘要:
A series of magnetite (Fe3O4) nanoparticles with different magnetic properties were prepared with the different Fe3+/Fe2+ molar ratios by coprecipitation process, and their inductive heat properties were measured by an alternating current (AC) magnetic field (80kHz, 30kA/m) for local hyperthermia. The specific saturation magnetization Ms of Fe3O4 nanoparticles prepared by coprecipitation is 65.53 emu/g under the optimum conditions of Fe3+:Fe2+ molar ratio at 1.8:1. The Ms of Fe3O4 nanoparticles decreased with the increasing of Fe3+/Fe2+ molar ratio. But the coercivity He increased with the increasing of Fe3+/Fe2+ molar ratio. The temperatures that different kinds of Fe3O4 nanoparticles physiological saline suspensions with concentration of 20 mg/ml reached were 4297.5 degrees C in the AC magnetic field during 29 minutes. The inductive heat property of Fe3O4 nanoparticles decreased with the increasing of the coercivity He, but increased with the increasing of specific saturation magnetization Ms in AC magnetic field. The Fe3O4 nanoparticles are perfect thermoseeds for local hyperthermia treatment of cancers with the super magnetic and inductive heat property.

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出版当年[2006]版:
大类 | 4 区 工程技术
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出版当年[2005]版:
Q3 MATERIALS SCIENCE, CERAMICS Q4 MATERIALS SCIENCE, COMPOSITES
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影响因子: 最新[2023版] 最新五年平均[2021-2025] 出版当年[2005版] 出版当年五年平均[2001-2005] 出版前一年[2004版]

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第一作者单位: [1]Beijing Univ Chem Technol, State Key Lab Chem Resource Engn, Beijing 100029, Peoples R China
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