The magnetite (Fe3O4) nanoparticles were prepared by coprecipitation of Fe3+ and Fe2+ with an aqueous NaOH solution. The Fe3O4/polyaniline (PANI) magnetic composite nanoparticles with a core-shell structure with a diameter of 30-50 nm were prepared via an in situ polymerization of aniline in an aqueous solution containing the Fe3O4 magnetic fluid. The inductive heat property of Fe3O4/PANI composite nanoparticles in an alternating current (ac) magnetic field was investigated. The potential of Fe3O4/PANI nanoparticles was evaluated for localized hyperthermia treatment of cancers. The saturation magnetization, Ms, and coercivity, Hc, are 50.05 emu g(-1) and 137 Oe for Fe3O4 nanoparticles and 26.34 emu g(-1) and 0 Oe for Fe3O4/PANI composite nanoparticles, respectively. Exposed in the ac magnetic field for 29 min, the temperatures of physiological saline suspensions containing Fe3O4 nanoparticles or Fe3O4/ PANI composite nanoparticles are 63.6 degrees C and 52.4 degrees C, respectively. The Fe3O4/ PANI composite nanoparticles would be useful as good thermoseeds for localized hyperthermia treatment of cancers.
第一作者单位：[1]Beijing Univ Chem Technol, State Key Lab Chem Resource Engn, Beijing 100029, Peoples R China
通讯作者：
推荐引用方式(GB/T 7714)：
Zhao Dong-Lin,Zhang Hai-Long,Zeng Xian-Wei,et al.Inductive heat property of Fe3O4/polymer composite nanoparticles in an ac magnetic field for localized hyperthermia[J].BIOMEDICAL MATERIALS.2006,1(4):198-201.doi:10.1088/1748-6041/1/4/004.
APA：
Zhao, Dong-Lin,Zhang, Hai-Long,Zeng, Xian-Wei,Xia, Qi-Sheng&Tang, Jin-Tian.(2006).Inductive heat property of Fe3O4/polymer composite nanoparticles in an ac magnetic field for localized hyperthermia.BIOMEDICAL MATERIALS,1,(4)
MLA：
Zhao, Dong-Lin,et al."Inductive heat property of Fe3O4/polymer composite nanoparticles in an ac magnetic field for localized hyperthermia".BIOMEDICAL MATERIALS 1..4(2006):198-201
