Magnetite (Fe3O4) nanoparticles with different magnetic properties were prepared by coprecipitation of Fe3+ and Fe2+, with aqueous NaOH solution. The inductive heat properties of Fe3O4 nanoparticles in an alternating current (AC) magnetic field were investigated for local hyperthermia. The maximum saturation magnetization MS of Fe3O4 nanoparticles is 65. 53 emu center dot g(-1) under the optimum conditions of Fe3+: Fe2+ molar ratio at 1.8:1. The M-s of Fe3O4 nanoparticles decreased as the Fe3+/Fe2+ molar ratio increased. But the coercivity H-c increases with the increasing of Fe3+/Fe2+ molar ratio. Exposed in the AC magnetic field for 29 min, the temperatures of physiological saline suspension containing Fe3O4 nanoparticles were 42-97.5 degrees C. The inductive heat property of Fe3O4 nanoparticles in AC magnetic field decreases as H-c increases, but increases with the increasing of M-s. The Fe3O4 nanoparticles would be useful as good thermoseeds for localized hyperthermia treatment of cancers.
第一作者单位:[1]Beijing Univ Chem Technol, State Key Lab Chem Resource Engn, Beijing 100029, Peoples R China
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推荐引用方式(GB/T 7714):
Zhao Donglin,Zeng Xianwei,Xia Qisheng,et al.Inductive heat property of Fe3O4 nanoparticles in AC magnetic field for local hyperthermia[J].RARE METALS.2006,25:621-625.doi:10.1016/S1001-0521(07)60159-4.
APA:
Zhao Donglin,Zeng Xianwei,Xia Qisheng&Tang Jintian.(2006).Inductive heat property of Fe3O4 nanoparticles in AC magnetic field for local hyperthermia.RARE METALS,25,
MLA:
Zhao Donglin,et al."Inductive heat property of Fe3O4 nanoparticles in AC magnetic field for local hyperthermia".RARE METALS 25.(2006):621-625