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Inductive heat property of Fe3O4 nanoparticles in AC magnetic field for local hyperthermia

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单位: [1]Beijing Univ Chem Technol, State Key Lab Chem Resource Engn, Beijing 100029, Peoples R China [2]Beijing Univ Chem Technol, Inst Carbon Fiber & Composites, Beijing 100029, Peoples R China [3]China Japan Friendship Hosp, Inst Clin Med Sci, Beijing 100029, Peoples R China [4]Tsing Hua Univ, Sch Med, Beijing 100084, Peoples R China
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关键词: magnetite nanoparticles local hyperthermia cancer treatment biomedical applications

摘要:
Magnetite (Fe3O4) nanoparticles with different magnetic properties were prepared by coprecipitation of Fe3+ and Fe2+, with aqueous NaOH solution. The inductive heat properties of Fe3O4 nanoparticles in an alternating current (AC) magnetic field were investigated for local hyperthermia. The maximum saturation magnetization MS of Fe3O4 nanoparticles is 65. 53 emu center dot g(-1) under the optimum conditions of Fe3+: Fe2+ molar ratio at 1.8:1. The M-s of Fe3O4 nanoparticles decreased as the Fe3+/Fe2+ molar ratio increased. But the coercivity H-c increases with the increasing of Fe3+/Fe2+ molar ratio. Exposed in the AC magnetic field for 29 min, the temperatures of physiological saline suspension containing Fe3O4 nanoparticles were 42-97.5 degrees C. The inductive heat property of Fe3O4 nanoparticles in AC magnetic field decreases as H-c increases, but increases with the increasing of M-s. The Fe3O4 nanoparticles would be useful as good thermoseeds for localized hyperthermia treatment of cancers.

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出版当年[2005]版:
大类 | 4 区 工程技术
最新[2025]版:
大类 | 1 区 材料科学
小类 | 1 区 材料科学:综合 1 区 冶金工程
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出版当年[2004]版:
Q3 METALLURGY & METALLURGICAL ENGINEERING Q4 MATERIALS SCIENCE, MULTIDISCIPLINARY
最新[2024]版:
Q1 MATERIALS SCIENCE, MULTIDISCIPLINARY Q1 METALLURGY & METALLURGICAL ENGINEERING

影响因子: 最新[2024版] 最新五年平均[2021-2025] 出版当年[2004版] 出版当年五年平均[2000-2004] 出版前一年[2003版] 出版后一年[2005版]

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第一作者单位: [1]Beijing Univ Chem Technol, State Key Lab Chem Resource Engn, Beijing 100029, Peoples R China
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