单位：[1]Chinese Acad Prevent Med, Inst Virol, Div Enter Viruses, Beijing 100052, Peoples R China[2]Beijing Friendship Hosp, Beijing, Peoples R China首都医科大学附属北京友谊医院[3]Changchun Childrens Hosp, Changchun, Peoples R China[4]Lulong Anti Epidem Stn, Qinhuangdao, Peoples R China[5]Kunming Childrens Hosp, Kunming, Peoples R China[6]Fujian Anti Epidem Stn, Fuzhou, Peoples R China[7]Guangzhou Childrens Hosp, Guangzhou, Peoples R China[8]Zhejiang Anti Epidem Stn, Hangzhou, Peoples R China[9]Zhengzhou Childrens Hosp, Zhengzhou, Peoples R China[10]Lanzhou Med Coll, Lanzhou, Peoples R China[11]Sichuan Anti Epidem Stn, Chengdu, Peoples R China[12]Ctr Dis Control & Prevent, Viral Gastroenteritis Sect, Atlanta, GA USA[13]WHO, Dept Vaccines & Biol, Geneva, Switzerland[*1]Chinese Acad Prevent Med, Inst Virol, Div Enter Viruses, 100 Ying Xin Jic,Xuan Wu Qu, Beijing 100052, Peoples R China
As part of a national rotavirus surveillance activity, we collected fecal specimens from 3,177 children with acute diarrhea in 10 regions of China between April 1998 and April 2000 and screened them for rotavirus. Rotavirus was detected in 41% (n=1,305) of specimens, and in these, G1 was the predominant serotype (72.6%), followed by G3 (14.2%), G2 (12.1%), G4 (2.5%), G9 (0.9%), and G untypeable (0.7%). Among 327 G-typed strains tested for P genotype, 14 different P.G combinations were identified, with the globally common strains P[8]G1, P[4]G2, P[8]G3, and P[8]G4 representing 75.6% of all typed rotavirus strains. Among the uncommon strains, 11 were P[6]G9, and others included P[6]G1, P[6]G3, and five novel P-G combinations (P[9]G1,P[4]G1, P[4]G3, P[4]G4, and P[8]G2). Our results indicate that while the common rotavirus strains remain predominant, the diversity of strains is much greater than was previously recognized.
第一作者单位：[*1]Chinese Acad Prevent Med, Inst Virol, Div Enter Viruses, 100 Ying Xin Jic,Xuan Wu Qu, Beijing 100052, Peoples R China
通讯作者：
通讯机构：[*1]Chinese Acad Prevent Med, Inst Virol, Div Enter Viruses, 100 Ying Xin Jic,Xuan Wu Qu, Beijing 100052, Peoples R China
推荐引用方式(GB/T 7714)：
Fang ZY,Yang H,Qi J,et al.Diversity of rotavirus strains among children with acute diarrhea in China: 1998-2000 surveillance study[J].JOURNAL of CLINICAL MICROBIOLOGY.2002,40(5):1875-1878.doi:10.1128/JCM.40.5.1875-1878.2002.
APA：
Fang, ZY,Yang, H,Qi, J,Zhang, J,Sun, LW...&Gentsch, JR.(2002).Diversity of rotavirus strains among children with acute diarrhea in China: 1998-2000 surveillance study.JOURNAL of CLINICAL MICROBIOLOGY,40,(5)
MLA：
Fang, ZY,et al."Diversity of rotavirus strains among children with acute diarrhea in China: 1998-2000 surveillance study".JOURNAL of CLINICAL MICROBIOLOGY 40..5(2002):1875-1878
