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EXPERIMENTAL STUDIES ON ELECTROLYTIC DOSAGE OF ECT FOR DOGS ESOPHAGEAL INJURY AND CLINICAL EFFECTS OF ECT FOR ESOPHAGEAL ANASTOMOTIC OPENING STENOSIS AND ESOPHAGEAL-CARCINOMA

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单位: [1]CHINA JAPAN FRIENDSHIP HOSP,DEPT THORAC SURG,BEIJING 100029,PEOPLES R CHINA
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关键词: ELECTROCHEMICAL THERAPY (ECT) CANCER ESOPHAGEAL STENOSIS

摘要:
Experimental and clinical studies have been performed to explore the potential benefits of electrochemical therapy (ECT) in oesophageal cancer. In a dog experiment, the oesophageal injury induced by ECT was evaluated. The provision of 7.5 volts (V) and 25-100 coulomb (C) was associated with a slight injury of the mucosa, which was completely healed after two weeks. Ten patients with oesophageal stenosis were treated with ECT (4.5-5.5 V, 20-50 mA and 85-180 C). In all patients there was significant dilatation of the stenotic area and the patients could eat a normal diet after three to four weeks. The clinical effectiveness in 35 patients treated with ECT for inoperable oesophageal carcinoma was found to be satisfactory. Complete and partial response was obtained in 15 cases (42.8%), and dysphagia was relieved for five to 13 months. In conclusion, oesophageal cancer may be successfully treated with a specially designed electrode and a specified dosage of electricity.

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