A comparison and review of three sets of classification criteria for systemic lupus erythematosus for distinguishing systemic lupus erythematosus from pure mucocutaneous manifestations in the lupus disease spectrum
单位：[1]Department of Dermatology, Hunan Key Laboratory of Medical Epigenomics, The Second Xiangya Hospital, Central South University, Changsha, China.[2]Research Unit of Key Technologies of Immune-Related Skin Diseases Diagnosis and Treatment, Chinese Academy of Medical Sciences (2019RU027), Changsha, China.[3]Department of Medical CosmetoIogy, Heping Hospital Affiliated to Changzhi Medical College, Changzhi, China.[4]Department of Rheumatology and Immunology, The Second Xiangya Hospital, Central South University, Changsha, China.[5]Department of Rheumatology and Immunology, Xiangya Hospital of Central South University, Changsha, China.[6]Department of Dermatology, Institute of Dermatology, The First Affiliated Hospital, Anhui Medical University, Hefei, China.[7]Department of Dermatology, China-Japan Friendship Hospital, Beijing, China.[8]Department of Dermatology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.[9]Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing, China.[10]Department of Rheumatology and Immunology, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, China.[11]Department of Dermatology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China.中山大学附属第二医院[12]Department of Dermatology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.浙江大学医学院附属第一医院[13]Department of Dermatology and Venereology, Nanfang Hospital, Southern Medical University, Guangzhou, China.[14]Department of Dermatology, The Second Affiliated Hospital of Kunming Medical University, Kunming, China.[15]Department of Dermatology, Peking University People's Hospital, Beijing, China.[16]Department of Dermatology, The Second Affiliated Hospital of Harbin Medical University, Harbin, China.[17]Department of Dermatology, The People's Hospital of Xinjiang Uyghur Autonomous Region, Urumqi, China.[18]Department of nephropathy and Rheumatology, The First People's Hospital of ChenZhou, ChenZhou, China.[19]Laboratory of Children's Kidney Disease, Children's Medical Center, The Second Xiangya Hospital, Central South University, Changsha, China.[20]Department of Nephropathy and Rheumatology, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, Changsha, China.[21]Department of Dermatology, Qilu Hospital of Shandong University, Jinan, China.[22]Department of Medical cosmetology, First Affiliated Hospital, University of South China, Hengyang, China.[23]Department of Rheumatology, Beijing Hospital, National Center of Gerontology, Beijing, China.[24]Department of Dermatology, Chongqing Traditional Chinese Medicine Hospital, Chongqing First People's Hospital, Chongqing, China.[25]Department of Dermatology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology (HUST), Wuhan, China.华中科技大学同济医学院附属协和医院[26]Department of Dermatology, First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.[27]Department of Dermatology, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, School of Clinical Medicine, Henan University, Zhengzhou, China.[28]Department of Rheumatology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.院本部南沙医院内科风湿免疫科内科风湿免疫科中山大学附属第一医院[29]Department of Dermatology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.重庆医科大学附属第一医院[30]Department of Dermatology, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.中山大学附属第三医院[31]Department of Dermatology, Heilongjiang Provincial Hospital, Harbin, China.[32]Department of Dermatology, Institute of Surgery Research, Daping Hospital, Army Medical University, Chongqing, China.[33]Department of Dermatology, the Seventh People's Hospital of Shenyang, Shenyang, China.[34]Department of Dermatology, Renmin Hospital of Wuhan University, Wuhan, China.[35]Department of Dermatology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.[36]Department of Dermatology, The First Hospital of Hebei Medical University, Shijiazhuang, China.[37]Department of epidemiology, Medical School of Hunan Normal University, Changsha, China.
Although the original purpose of the systemic lupus erythematosus (SLE) classification criteria was to distinguish SLE from other mimic diseases, and to facilitate sample selection in scientific research, they have become widely used as diagnostic criteria in clinical situations. It is not known yet if regarding classification criteria as diagnostic criteria, what problems might be encountered? This is the first study comparing the three sets of classification criteria for SLE, the 1997 American College of Rheumatology (ACR'97), 2012 Systemic Lupus International Collaborating Clinics (SLICC'12) and 2019 European League Against Rheumatism/American College of Rheumatology (EULAR/ACR'19), for their ability to distinguish patients with SLE from patients with pure mucocutaneous manifestations (isolated cutaneous lupus erythematosus without internal disease, i-CLE) in the lupus disease spectrum. 1,865 patients with SLE and 232 patients with i-CLE were recruited from a multicenter study. We found that, due to low specificity, none of the three criteria are adept at distinguishing patients with SLE from patients with i-CLE. SLICC'12 performed best among the original three criteria, but if a positive ANA was removed as an entry criterion, EULAR/ACR'19 would performed better. A review of previous studies that compared the three sets of criteria was presented in this work.
第一作者单位：[1]Department of Dermatology, Hunan Key Laboratory of Medical Epigenomics, The Second Xiangya Hospital, Central South University, Changsha, China.[2]Research Unit of Key Technologies of Immune-Related Skin Diseases Diagnosis and Treatment, Chinese Academy of Medical Sciences (2019RU027), Changsha, China.
通讯作者：
通讯机构：[1]Department of Dermatology, Hunan Key Laboratory of Medical Epigenomics, The Second Xiangya Hospital, Central South University, Changsha, China.[2]Research Unit of Key Technologies of Immune-Related Skin Diseases Diagnosis and Treatment, Chinese Academy of Medical Sciences (2019RU027), Changsha, China.[*1]Department of Dermatology, Hunan Key Laboratory of Medical Epigenomics, The Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, China[*2]Research Unit of Key Technologies of Immune-related Skin Diseases Diagnosis and Treatment, Chinese Academy of Medical Sciences (2019RU027), Changsha, Hunan 410011, China.
推荐引用方式(GB/T 7714)：
Jin Hui,Huang Tao,Wu Ruifang,et al.A comparison and review of three sets of classification criteria for systemic lupus erythematosus for distinguishing systemic lupus erythematosus from pure mucocutaneous manifestations in the lupus disease spectrum[J].LUPUS.2020,29(14):1854-1865.doi:10.1177/0961203320959716.
APA：
Jin Hui,Huang Tao,Wu Ruifang,Zhao Ming,Wu Haijing...&Lu Qianjin.(2020).A comparison and review of three sets of classification criteria for systemic lupus erythematosus for distinguishing systemic lupus erythematosus from pure mucocutaneous manifestations in the lupus disease spectrum.LUPUS,29,(14)
MLA：
Jin Hui,et al."A comparison and review of three sets of classification criteria for systemic lupus erythematosus for distinguishing systemic lupus erythematosus from pure mucocutaneous manifestations in the lupus disease spectrum".LUPUS 29..14(2020):1854-1865
