单位：[1]Department of Pulmonary and Critical Care Medicine, Center of Respiratory Medicine, China-Japan Friendship Hospital, Beijing, China.[2]Institute of Respiratory Medicine, Chinese Academy of Medical Sciences, Beijing, China.[3]National Clinical Research Center for Respiratory Diseases , Beijing, China.[4]Department of Pulmonary and Critical Care Medicine, Affiliated Hospital of Jianghan University, Hubei, China.[5]Capital Medical University, Beijing, China.[6]Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.
Aim: Patients with acute infectious diseases are at an increased risk of venous thromboembolism (VTE). Clinicians should be aware of the VTE risk in patients with COVID-19, many of whom present with severe coagulation disorders. Method: We used an online platform to conduct a cross-sectional questionnaire survey among doctors in mainland China in March 2020. The questionnaire was designed to figure out the clinician's current awareness of VTE prevention and detection rates, as well as the current status of VTE prophylaxis in patients with COVID-19. Results: We collected 1,636 replies, of which 1,579 were valid. Among these, 991 (63%) clinicians were involved directly in frontline treatment. Most of the clinicians (1,492, or 94%) thought it was necessary to assess the VTE risk in patients with COVID-19. However, only 234 (24%) clinicians performed appropriate assessment during the COVID-19 outbreak. For patients with mild/moderate COVID-19, 752 (76%) clinicians would prescribe exercise and water to prevent VTE. For patients with severe COVID-19, 448 (45%) clinicians would prescribe mechanical devices if the patient had a high bleeding risk, and 648 (65%) clinicians would choose LMWH as prophylaxis if the patient had a low bleeding risk. The VTE detection rate was not that high in both mild/moderate and severe patients. Conclusion: Although most clinicians recommended prescribing VTE prophylaxis to patients with COVID-19, the practice still needs to be improved. A real-world registry to investigate the true incidence of VTE, and the effect of prescribing appropriate prophylaxis for patients with COVID-19, is necessary in the future.
基金：
Chinese Academy of Engineering emergency research and cultivation project for COVID-19 [2020-KYGG-01-05]; Fund of The National Key Research and Development Program of China [2016YFC0905600, 2016YFC0901104]; CAMS Innovation Fund for Medical Sciences(CIFMS) [2018-I2M-1-003]
第一作者单位：[1]Department of Pulmonary and Critical Care Medicine, Center of Respiratory Medicine, China-Japan Friendship Hospital, Beijing, China.[2]Institute of Respiratory Medicine, Chinese Academy of Medical Sciences, Beijing, China.[3]National Clinical Research Center for Respiratory Diseases , Beijing, China.
共同第一作者：
通讯作者：
通讯机构：[1]Department of Pulmonary and Critical Care Medicine, Center of Respiratory Medicine, China-Japan Friendship Hospital, Beijing, China.[2]Institute of Respiratory Medicine, Chinese Academy of Medical Sciences, Beijing, China.[3]National Clinical Research Center for Respiratory Diseases , Beijing, China.[*1]Department of Pulmonary and Critical Care Medicine Center of Respiratory Medicine, China-Japan Friendship Hospital, Beijing, China, Institute of Respiratory Medicine, Chinese Academy of Medical Sciences, Beijing, China, National Clinical Research Center for Respiratory Diseases, Beijing, China
推荐引用方式(GB/T 7714)：
Zhu Zhang,Linfeng Xi,Shuai Zhang,et al.Awareness and Prophylaxis of Venous Thromboembolism in Patients with COVID-19: A National Cross-Sectional Survey in Epidemic Era[J].JOURNAL of ATHEROSCLEROSIS and THROMBOSIS.2020,27(10):1123-1137.doi:10.5551/jat.58933.
APA：
Zhu Zhang,Linfeng Xi,Shuai Zhang,Yunxia Zhang,Wenyi Pang...&Chen Wang.(2020).Awareness and Prophylaxis of Venous Thromboembolism in Patients with COVID-19: A National Cross-Sectional Survey in Epidemic Era.JOURNAL of ATHEROSCLEROSIS and THROMBOSIS,27,(10)
MLA：
Zhu Zhang,et al."Awareness and Prophylaxis of Venous Thromboembolism in Patients with COVID-19: A National Cross-Sectional Survey in Epidemic Era".JOURNAL of ATHEROSCLEROSIS and THROMBOSIS 27..10(2020):1123-1137
