单位：[1]Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, National Clinical Research Center for Digestive Diseases, Beijing Digestive Disease Center, Beijing Key Laboratory for Precancerous Lesion of Digestive Diseases, China临床科室国家中心消化分中心消化内科首都医科大学附属北京友谊医院
Emerging evidence has shown that aberrantly expressed long noncoding RNAs (lncRNAs) play a vital role in various biological processes of tumorigenesis. Bladder cancer associated transcript 1 (BLACAT1) is a novel lncRNA located on chromosome 1q32.1, which regulated multiple downstream targets via serving as a "sponge" for their corresponding microRNAs or by directly interacting with various regulating proteins. In this review, we summarized the role of BLACAT1 in the development and progression of different cancers. We also highlighted that BLACAT1 could be utilized as a potential biomarker and therapeutic target for human cancers.
基金：
National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81702314, 81802310]; Beijing Science and Technology Nova Program [Z191100001119128]; Beijing Municipal Science and Technology Project [Z191100006619081]; Digestive Medical Coordinated Development Center of Beijing Municipal Administration of Hospitals [XXZ02, XXZ01]
语种：
外文
被引次数：
WOS：
PubmedID：
中科院(CAS)分区：
出版当年[2019]版：
大类|3 区医学
小类|3 区医学：研究与实验3 区药学
最新[2025]版：
大类|2 区医学
小类|2 区医学：研究与实验2 区药学
JCR分区：
出版当年[2018]版：
Q1PHARMACOLOGY & PHARMACYQ2MEDICINE, RESEARCH & EXPERIMENTAL
最新[2023]版：
Q1MEDICINE, RESEARCH & EXPERIMENTALQ1PHARMACOLOGY & PHARMACY
第一作者单位：[1]Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, National Clinical Research Center for Digestive Diseases, Beijing Digestive Disease Center, Beijing Key Laboratory for Precancerous Lesion of Digestive Diseases, China
通讯作者：
通讯机构：[1]Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, National Clinical Research Center for Digestive Diseases, Beijing Digestive Disease Center, Beijing Key Laboratory for Precancerous Lesion of Digestive Diseases, China[*1]No. 95, Yongan Road, Xicheng District, Beijing, 100050, China.
推荐引用方式(GB/T 7714)：
Min Zhu,Xiao Li,Shengtao Zhu,et al.Long non-coding RNA BLACAT1, a novel promising biomarker and regulator of human cancers[J].BIOMEDICINE & PHARMACOTHERAPY.2020,132:doi:10.1016/j.biopha.2020.110808.
APA：
Min Zhu,Xiao Li,Shengtao Zhu,Peng Li,Li Min&Shutian Zhang.(2020).Long non-coding RNA BLACAT1, a novel promising biomarker and regulator of human cancers.BIOMEDICINE & PHARMACOTHERAPY,132,
MLA：
Min Zhu,et al."Long non-coding RNA BLACAT1, a novel promising biomarker and regulator of human cancers".BIOMEDICINE & PHARMACOTHERAPY 132.(2020)
