高级检索
当前位置: 首页 > 详情页

Effectiveness and safety of light vegetarian diet and Qingjiang Tiaochang Recipe for functional constipation An exploratory study protocol for randomized controlled trial

文献详情

资源类型:
WOS体系:

收录情况: ◇ SCIE

单位: [1]School of Graduates, Beijing University of Chinese Medicine, Beijing, China. [2]Department of Gastroenterology of Traditional Chinese Medicine, China-Japan Friendship Hospital, Beijing, China. [3]Peking University China-Japan Friendship School of Clinical Medicine, Peking University, Beijing, China. [4]Department of Pharmacy, China-Japan Friendship Hospital, Beijing, China.
出处:
ISSN:

关键词: clinical trials functional constipation herbal medicine RCT vegetarian

摘要:
Introduction: Functional constipation is a chronic disease that is common in children and adults around the world. The treatments for functional constipation include diet and lifestyle interventions, medications, and surgery. The diet pattern plays an important role in the occurrence of constipation. We found in clinical practice that simple application of drugs cannot achieve long-term relief of constipation, and a large number of patients are not satisfied with the existing treatment. We have concluded that Qingjiang Tiaochang Recipe (QJTCR) and light vegetarian diet (LVD) can effectively improve constipation. However, there is no enough evidence for the description of the effect. This protocol aims at exploratorily investigating effectiveness and safety of LVD and QJTCR following a rigorous clinical trial. Methods and analysis: We will recruit 90 patients to participate in this prospective, placebo-controlled, randomized trial, and exploratory study at the China-Japan Friendship Hospital, including traditional Chinese medicine group, placebo + diet group, traditional Chinese medicine + diet group. Patients in the diet intervention group must strictly abide by LVD, and the study will continue for 28 days. During the intervention period, we need to record a designed diary to assess diet quality and defecation. The primary outcomes for this clinical study were weekly complete spontaneous bowel movements. The secondary outcomes were constipation-related symptom rating scale, traditional Chinese medicine syndrome scale, and 48-hour gastrointestinal transit time, high-resolution anorectal manometry, Bristol stool score, constipation quality of life assessment scale, constipation symptoms self-assessment scale, short-chain fatty acids in feces. In addition, the study will determine the safety of the intervention.

基金:
语种:
被引次数:
WOS:
中科院(CAS)分区:
出版当年[2019]版:
大类 | 4 区 医学
小类 | 3 区 医学:内科
最新[2025]版:
大类 | 4 区 医学
小类 | 4 区 医学:内科
JCR分区:
出版当年[2018]版:
Q2 MEDICINE, GENERAL & INTERNAL
最新[2023]版:
Q2 MEDICINE, GENERAL & INTERNAL

影响因子: 最新[2023版] 最新五年平均[2021-2025] 出版当年[2018版] 出版当年五年平均[2014-2018] 出版前一年[2017版] 出版后一年[2019版]

第一作者:
第一作者单位: [1]School of Graduates, Beijing University of Chinese Medicine, Beijing, China. [2]Department of Gastroenterology of Traditional Chinese Medicine, China-Japan Friendship Hospital, Beijing, China.
通讯作者:
通讯机构: [2]Department of Gastroenterology of Traditional Chinese Medicine, China-Japan Friendship Hospital, Beijing, China. [*1]China-Japan Friendship Hospital, Beijing 100029, China
推荐引用方式(GB/T 7714):
APA:
MLA:

资源点击量:1320 今日访问量:0 总访问量:816 更新日期:2025-04-01 建议使用谷歌、火狐浏览器 常见问题

版权所有:重庆聚合科技有限公司 渝ICP备12007440号-3 地址:重庆市两江新区泰山大道西段8号坤恩国际商务中心16层(401121)