Objective: Breast cancer (BC) in young women tends to be more aggressive. This study highlights the clinicopathological features and outcomes of young breast cancer (YBC) patients in a developing country. Methods: Consecutive patients aged 35 years or younger with a pathologically confirmed diagnosis of breast cancer treated and followed up at our department were included. Medical records and follow-up databases were reviewed and documented. Results: The rate of breast conservation and reconstruction surgery is higher in YBC patients. YBC patients are more likely to have tumors over 5cm, high-grade, hormone receptor negative, triple negative and stage III than old patients. There was no statistically significant difference in the pathological type, lymph node metastasis, and HER2 status. The median follow-up time was 96 months. The disease-free survival (DFS) was significantly worse in the YBC group. However, the overall survival (OS) had no difference between the two groups. Conclusion: YBC patients had more aggressive pathological features, such as hormone receptor negative, triple negative, high-grade and advanced stage, and poorer DFS than the old counterparts.
第一作者单位:[1]Department of General Surgery, China- Japan Friendship Hospital, Beijing, People’s Republic of China
通讯作者:
通讯机构:[1]Department of General Surgery, China- Japan Friendship Hospital, Beijing, People’s Republic of China[*1]Department of General Surgery, China- Japan Friendship Hospital, No. 2 Yinghua East Road, Chaoyang District, Beijing, 100029, People’s Republic of China
推荐引用方式(GB/T 7714):
Sun Xiaoliang,Liu Jun,Ji Haoyang,et al.Clinicopathological Characteristics and Prognosis of Breast Cancer in Young Women - A Single Center Study in a Developing Country[J].CANCER MANAGEMENT and RESEARCH.2021,13:1601-1607.doi:10.2147/CMAR.S299066.
APA:
Sun, Xiaoliang,Liu, Jun,Ji, Haoyang,Yang, Meng&Lu, Yao.(2021).Clinicopathological Characteristics and Prognosis of Breast Cancer in Young Women - A Single Center Study in a Developing Country.CANCER MANAGEMENT and RESEARCH,13,
MLA:
Sun, Xiaoliang,et al."Clinicopathological Characteristics and Prognosis of Breast Cancer in Young Women - A Single Center Study in a Developing Country".CANCER MANAGEMENT and RESEARCH 13.(2021):1601-1607