单位:[1]School of Biomedical Engineering and Technology, Tianjin Medical University, Tianjin 300070, China[2]The School of Science, Tianjin University of Technology and Education, Tianjin 300222, China[3]Liver Research Center, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China临床科室国家中心肝病分中心首都医科大学附属北京友谊医院[4]Beijing Key Laboratory of Translational Medicine in Liver Cirrhosis and National Clinical Research Center of Digestive Disease, Beijing 100050, China
Propagation-based X-ray phase-contrast computed tomography (PB-PCCT) can serve as an effective tool for studying organ function and pathologies. However, it usually suffers from a high radiation dose due to the long scan time. To alleviate this problem, we propose a deep learning reconstruction framework for PB-PCCT with sparse-view projections. The framework consists of dual-path deep neural networks, where the edge detection, edge guidance, and artifact removal models are incorporated into two sub-networks. It is worth noting that the framework has the ability to achieve excellent performance by exploiting the data-based knowledge of the sample material characteristics and the model-based knowledge of PB-PCCT. To evaluate the effectiveness and capability of the proposed framework, simulations and real experiments were performed. The results demonstrated that the proposed framework could significantly suppress streaking artifacts and produce high-contrast and high-resolution computed tomography images. (C) 2021 Optical Society of America
基金:
National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [82071922, 81671683, 81670545]; Natural Science Foundation of Tianjin CityNatural Science Foundation of Tianjin [16JCYBJC28600]; TianjinMunicipal Education Commission [2020KJ208]