单位：[1]National Integrated Traditional and Western Medicine Center for Cardiovascular Disease, China–Japan Friendship Hospital, Beijing, China[2]Department of Cardiology, Shenzhen Traditional Chinese medicine hospital, Shenzhen, China深圳市康宁医院深圳医学信息中心[3]Department of Traditional Chinese medicine, Beijing Fuxing Hospital, Capital Medical University, Beijing, China[4]Graduate School, Beijing University of Chinese Medicine, Beijing, China[5]Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Science. Xiangyang, China[6]Department of Cardiology, Jiangmen Wuyi Hospital of Traditional Chinese medicine, Jiangmen, China.
Background: Modern clinical trials and experimental researches of traditional Chinese medicine (TCM) have been conducted for decades and provided support for the prevention and treatment of acute coronary syndrome (ACS). However the level of evidence and the proper application of TCM were still barely satisfactory. Methods: In this study, we divided ACS into 3 different stages, including unstable angina, acute myocardial infarction, and post myocardial infarction. Then we systematically reviewed and meta-analyzed the existing randomized controlled trials on both clinical manifestations and objective indicators, in these 3 aspects. Results: The results indicate that TCM can both improve the clinical manifestations and ameliorate the objective parameters in different courses of ACS, including C-reactive protein in unstable angina, left ventricular ejection fraction in acute myocardial infarction and post myocardial infarction. And the incidence of short-term cardiovascular events are lower in TCM intervention group. Some of the improvements lead to potential long-term benefits. Conclusion: TCM treatment is beneficial to different courses of ACS. To acquire more solid and comprehensive evidence of TCM in treating ACS, more rigorously designed randomized controlled trials with longer follow-up duration are warranted.
基金：
National Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81803923, 81904187, 81903988]; Young Elite Scientists Sponsorship Program by CAST [2018QNRC2-C10, 2017QNRC1-02]; Science Research Fund of China-Japan Friendship Hospital [2017-2-QN-13]
第一作者单位：[1]National Integrated Traditional and Western Medicine Center for Cardiovascular Disease, China–Japan Friendship Hospital, Beijing, China[*1]National Integrated Traditional and Western Medicine Center for Cardiovascular Disease, China–Japan Friendship Hospital, Beijing, China
共同第一作者：
通讯作者：
通讯机构：[1]National Integrated Traditional and Western Medicine Center for Cardiovascular Disease, China–Japan Friendship Hospital, Beijing, China[*1]National Integrated Traditional and Western Medicine Center for Cardiovascular Disease, China–Japan Friendship Hospital, Beijing, China
推荐引用方式(GB/T 7714)：
Liao Jiangquan,Li Tao,Hua Yingying,et al.Traditional Chinese medicine for acute coronary syndrome A meta-analysis of clinical manifestations and objective indicators[J].MEDICINE.2021,100(33):doi:10.1097/MD.0000000000026927.
APA：
Liao Jiangquan,Li Tao,Hua Yingying,Shao Mingjing,Wang Yan...&Du Jinhang.(2021).Traditional Chinese medicine for acute coronary syndrome A meta-analysis of clinical manifestations and objective indicators.MEDICINE,100,(33)
MLA：
Liao Jiangquan,et al."Traditional Chinese medicine for acute coronary syndrome A meta-analysis of clinical manifestations and objective indicators".MEDICINE 100..33(2021)
