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An evidence mapping of systematic reviews and meta-analysis on traditional Chinese medicine for ulcerative colitis

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单位: [1]Beijing Univ Chinese Med, Ctr Evidence Based Chinese Med, Beijing 100029, Peoples R China [2]China Acad Chinese Med Sci, Inst Basic Res Clin Med, Ctr Evidence Based Chinese Med, Beijing 100010, Peoples R China [3]China Japan Friendship Hosp, Dept Neurol, Beijing 100029, Peoples R China [4]Beijing Univ Chinese Med, Ctr Studies Constitut Res Tradit Chinese Med, Beijing 100029, Peoples R China
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关键词: Evidence-based medicine Mapping review AMSTAR 2 Herbal Digestion

摘要:
Background Traditional Chinese Medicine (TCM) has been a proposed treatment option for ulcerative colitis (UC), however it has been difficult to understand the breadth and depth of evidence as various Chinese medicine therapies may produce effects differently. The aim of this evidence mapping is to visually understand the available evidence in the use of TCM in the treatment of UC, and to identify gaps in evidence to inform priorities of future research. Methods A systematic electronic literature search of six databases were performed to identify systematic reviews (SRs) on different Chinese medicine therapies in the treatment in UC. Methodological quality of the included SRs was assessed using AMSTAR 2. Results The mapping was based on 73 SRs, which included nine interventions that met eligibility criteria. The quality of the included SRs was very low. The diseases stages of patients with UC varied greatly, from active to remission, to non-acute outbreak, to not reported. The results mostly favored the method of intervention. Oral administration combined with enema was the most widely used route of administration in secondary research. Conclusion Based on the current evidence, the treatment of UC with TCM can only be recommended cautiously. A majority of included SRs did not report the location of the disease, the disease classification, and the route of administration of the intervention. Further research is needed on the effectiveness of Chinese medicine alone in the treatment of UC. The effectiveness of combined Chinese and conventional medicine combined with different routes of administration cannot be confirmed. Attention should be paid to the methodological quality of the systematic review. Unifies the outcome indicators used in the evaluation of effectiveness.

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出版当年[2020]版:
最新[2025]版:
大类 | 3 区 医学
小类 | 2 区 全科医学与补充医学
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出版当年[2019]版:
最新[2023]版:
Q1 INTEGRATIVE & COMPLEMENTARY MEDICINE

影响因子: 最新[2023版] 最新五年平均[2021-2025] 出版当年[2019版] 出版当年五年平均[2015-2019] 出版前一年[2018版]

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第一作者单位: [1]Beijing Univ Chinese Med, Ctr Evidence Based Chinese Med, Beijing 100029, Peoples R China
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