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Comparative Effectiveness of Minimally Invasive Nonsurgical Treatments for Plantar Fasciitis: A Network Meta-analysis of 30 Randomized Controlled Trials

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单位: [1]Institute of Clinical Pharmacology, Xiyuan Hospital of China Academy of Chinese Medical Sciences, Beijing, China [2]Dept. of Orthopaedic and Trauma Surgery, Xiyuan Hospital, China Academy of Chinese Medical Science, Beijing, China [3]Dept. of Bone & Joint Surgery and Orthopedics, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China [4]School of Business and Management, Shanghai International Studies University, Shanghai, China [5]Dept. of Orthopaedics and Trauma Surgery, Hebei PetroChina Central Hospital, Langfang, China [6]Dept. of Orthopaedics and Trauma Surgery, University Hospital Bonn, Germany [7]Dept. of Orthopaedics, China-Japan Friendship Hospital, Beijing, China
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关键词: Plantar fasciitis randomized controlled trials network meta-analysis Bayesian analysis visual analog scale botulinum toxin A

摘要:
Background: Several minimally invasive nonsurgical treatments have been widely applied for plantar fasciitis (PF). To date, controversy still exists regarding the effectiveness of these approaches for treating PF. Objective: The purpose of this study was to perform a comprehensive comparison of the currently available invasive nonsurgical treatments for PF regarding short-and mid-term reductions in pain using a network meta-analysis (NMA). Study Design: NMA of randomized controlled trials (RCTs) for minimally invasive nonsurgical treatments of PF. Methods: The EMBASE, PubMed, and Cochrane Central Register of Controlled Trials (CENTRAL) databases were searched for eligible studies. Patients were adults age >= 18 years with PF. The outcome measures were the visual analog scale (VAS) scores at 3-6 weeks and 4-6 months. Pairwise meta-analysis and NMA based on a Bayesian analysis were performed, and all potential comparisons and rank of probabilities were calculated. Results: Thirty RCTs were included in the NMA. The trials investigated 20 treatments or combined treatments, including autologous whole blood, botulinum toxin A (BTA), ultrasound guided gastrocnemius injection of botulinum toxin (BTA in the gastrocnemius), corticosteroid (CS), miniscalpel-needle (MSN), placebo, platelet-rich plasma (PRP), and the ultrasound-guided technique and peppering technique (PEP). The MSN treatment may be the best choice. Limitations: Some treatments were investigated in only one study or at one follow-up period and were separated from the network at 4-6 months. Other limitations include the inconformity of the treatment schedule and dose. Conclusions: The MSN treatment should be recommended as the best therapy, followed by BTA in the gastrocnemius and BTA. CS and PRP are common medications that remain valuable in clinical practice. PEP can be performed after the injection of medication.

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出版当年[2020]版:
大类 | 3 区 医学
小类 | 3 区 麻醉学 3 区 临床神经病学
最新[2025]版:
大类 | 3 区 医学
小类 | 3 区 麻醉学 3 区 临床神经病学
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出版当年[2019]版:
Q2 ANESTHESIOLOGY Q2 CLINICAL NEUROLOGY
最新[2023]版:
Q2 ANESTHESIOLOGY Q2 CLINICAL NEUROLOGY

影响因子: 最新[2023版] 最新五年平均[2021-2025] 出版当年[2019版] 出版当年五年平均[2015-2019] 出版前一年[2018版] 出版后一年[2020版]

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第一作者单位: [1]Institute of Clinical Pharmacology, Xiyuan Hospital of China Academy of Chinese Medical Sciences, Beijing, China
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通讯机构: [2]Dept. of Orthopaedic and Trauma Surgery, Xiyuan Hospital, China Academy of Chinese Medical Science, Beijing, China [*1]Dept. of Orthopaedic and Trauma Surgery, Xiyuan Hospital, China [*2]Academy of Chinese Medical Science, Xiyuan Caochang 1, Haidian District 100091, Beijing, China
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