Prevalence of recommended anticoagulation by guidelines preadmission and its impact on the incidence of acute myocardial infarction (AMI) and in-hospital outcomes after AMI in atrial fibrillation patients
单位：[1]Cardiovascular Center, Beijing Tongren Hospital, Capital Medical University, No.1, Dong Jiao Min Xiang Street, Dongcheng District, Beijing 100730, China首都医科大学附属同仁医院[2]Department of Cardiology, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China[3]Emergency Department of China-Japan Friendship Hospital, No. 2 YinghuaDongjie, Hepingli, Chaoyang District, Beijing 100029, China[4]Trauma Center, Peking University People’s Hospital, Beijing 100044, China[5]Department of Ultrasound, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China医技科室影像中心超声医学科首都医科大学附属北京友谊医院
This study was designed to explore the prevalence of recommended anticoagulation by guidelines before admission and its impact on the incidence of acute myocardial infarction (AMI) and the AMI associated in-hospital outcomes in patients with atrial fibrillation (AF). 10,725 patients with AF at their first hospitalizations in our hospitals were retrospectively reviewed, with a prevalence of recommended anticoagulation preadmission 24.41% (Number = 2618). They had lower risk of AMI incidence (Adjusted OR 0.66, 95%CI 0.54-0.81, p < 0.001) compared to those without recommended anticoagulation after multivariate logistic regression. Furthermore, recommended anticoagulation preadmission reduced in-hospital all-cause death associated with AMI in univariate logistic analysis, but had no impact on the risk of in-hospital bleeding and stroke after AMI both in univariate and multivariate logistic analysis. The prevalence of recommended anticoagulation before admission was 24.41% in China. Recommended anticoagulation reduced incidence of hospitalized AMI, but had no impact on the associated in-hospital bleeding and stroke risk after AMI.
基金：
National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81800291]; Beijing Municipal Administration of Hospitals' Youth Programme [QML20180207]
第一作者单位：[1]Cardiovascular Center, Beijing Tongren Hospital, Capital Medical University, No.1, Dong Jiao Min Xiang Street, Dongcheng District, Beijing 100730, China
通讯作者：
推荐引用方式(GB/T 7714)：
Bai Ying,Liu Xin-Yao,Liu Yue,et al.Prevalence of recommended anticoagulation by guidelines preadmission and its impact on the incidence of acute myocardial infarction (AMI) and in-hospital outcomes after AMI in atrial fibrillation patients[J].JOURNAL of THROMBOSIS and THROMBOLYSIS.2022,doi:10.1007/s11239-021-02622-0.
APA：
Bai Ying,Liu Xin-Yao,Liu Yue,Guo Shi-Dong,Wang Zhen-Zhou...&Zhong Peng.(2022).Prevalence of recommended anticoagulation by guidelines preadmission and its impact on the incidence of acute myocardial infarction (AMI) and in-hospital outcomes after AMI in atrial fibrillation patients.JOURNAL of THROMBOSIS and THROMBOLYSIS,,
MLA：
Bai Ying,et al."Prevalence of recommended anticoagulation by guidelines preadmission and its impact on the incidence of acute myocardial infarction (AMI) and in-hospital outcomes after AMI in atrial fibrillation patients".JOURNAL of THROMBOSIS and THROMBOLYSIS .(2022)
