单位：[1]Department of Clinical Laboratory, Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, National Cancer Center/National Clinical Research Center for Cancer/State Key Laboratory of Molecular Oncology, Beijing, China[2]Department of Pulmonary and Critical Care Medicine, Center of Respiratory Medicine, China-Japan Friendship Hospital, Beijing, China[3]National Center for Respiratory Medicine, Beijing, China[4]Institute of Respiratory Medicine, Chinese Academy of Medical Sciences, Beijing, China[5]National Clinical Research Center for Respiratory Diseases, Beijing, China[6]Emergency department, China Japan Friendship Hospital, Beijing, China[7] Department of Pathology, China-Japan Friendship Hospital, Beijing, China[8]Department of internal medicine, China Nuclear Industry Beijing 401 Hospital, Beijing, China[9]Beijing University of Chinese Medicine, Beijing, China
Granulosa cell tumor (GCT) is a rare tumor that originates from neural/Schwann cells. GCTs can occur at any age and at any site in the body. The most common site is the tongue, followed by the mammary gland, upper respiratory tract ( throat and bronchus), and gastrointestinal tract (esophagus, large intestine and perianal area, stomach, small intestine, and bile duct). Malignant GCTs account for less than 1%-2% of all GCTs. Fewer than five GCTs in the thoracic wall have been reported, almost all of these benign. Here, we report a new case of malignant GCT of the thoracic wall, with rib invasion and pleural metastasis, in an Asian male. Microscopic examination revealed round, granular cells with eosinophilic cytoplasm and without prominent atypia. Despite these findings the disease showed rapid clinical progression. In summary, the tumor, although histologically 'benign', was clinically 'malignant'.
第一作者单位：[1]Department of Clinical Laboratory, Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, National Cancer Center/National Clinical Research Center for Cancer/State Key Laboratory of Molecular Oncology, Beijing, China
通讯作者：
通讯机构：[2]Department of Pulmonary and Critical Care Medicine, Center of Respiratory Medicine, China-Japan Friendship Hospital, Beijing, China[3]National Center for Respiratory Medicine, Beijing, China[4]Institute of Respiratory Medicine, Chinese Academy of Medical Sciences, Beijing, China[5]National Clinical Research Center for Respiratory Diseases, Beijing, China
推荐引用方式(GB/T 7714)：
Gao Shengnan,Xing Bin,Lichao Sun,et al.Malignant granular cell tumor in the thoracic wall: A case report[J].FRONTIERS IN ONCOLOGY.2022,12:doi:10.3389/fonc.2022.895924.
APA：
Gao, Shengnan,Xing, Bin,Lichao, Sun,Luo, Jie,Tang, Jiao...&Zhang, Xiaoyan.(2022).Malignant granular cell tumor in the thoracic wall: A case report.FRONTIERS IN ONCOLOGY,12,
MLA：
Gao, Shengnan,et al."Malignant granular cell tumor in the thoracic wall: A case report".FRONTIERS IN ONCOLOGY 12.(2022)
