单位：[1]Department of Rheumatology and Immunology, People’s Hospital,Peking University Health Science Center[2]Department ofRheumatology and Immunology, Peking University ShougangHospital[3]Department of Gastroenterology, People’s Hospital, PekingUniversity Health Science Center, Beijing[4]Department ofRheumatology and Immunology, Second Hospital of Shanxi MedicalUniversity, Taiyuan[5]Department of Rheumatology and Immunology,First Affiliated Hospital, Baotou Medical College, Baotou内蒙古科技大学包头医学院[6]Departmentof Rheumatology, China-Japan Friendship Hospital, Beijing[7]Department of Clinical Immunology, Xijing Hospital, Fourth MilitaryMedical University, Xi’an[8]Department of Rheumatology andImmunology, Second Hospital of Hebei Medical University,Shijiazhuang[9]Department of Rheumatology and Immunology, PekingUniversity Third Hospital, Beijing[10]Department of Rheumatology andImmunology, Third Hospital of Hebei Medical University, Shijiazhuang[11]Department of Rheumatology and Immunology, Affiliated KailuanHospital of North China Coal Medical University, Tangshan, Hebei[12]Department of Rheumatology and Clinical Immunology, PekingUniversity First Hospital, Beijing[13]Department of Rheumatologyand Immunology, Bethune International Peace Hospital of PLA,Shijiazhuang[14]Department of Rheumatology and Immunology,Handan Central Hospital, Handan[15]Department of Rheumatology and Immunology, People0s Hospital of Hebei Province, Shijiazhuang[16]Department of Rheumatology, People’s Hospital of GuangxiZhuang Autonomous Region, Nanning[17]Department ofRheumatology and Immunology, Beijing Shunyi Hospital, Beijing[18]Department of Rheumatology, Tongji Hospital, Tongji MedicalCollege, Huazhong University of Science and Technology, Wuhan华中科技大学同济医学院附属同济医院[19]Department of Rheumatology, First Affiliated Hospital, Sun Yat-senUniversity, Guangzhou院本部南沙医院内科风湿免疫科内科风湿免疫科中山大学附属第一医院[20]Department of Rheumatology andImmunology, Beijing Hospital, Beijing[21]Department of Rheumatology,Shandong University Qilu Hospital, Jinan[22]Deparment ofRheumatology, Second Hospital of Lanzhou University, Lanzhou,China
Objective. To evaluate the impact of RA on work capacity and identify factors related to work capacity impairment in patients with RA. Methods. A cross-sectional multicentre study was performed in 21 tertiary care hospitals across China. A consecutive sample of 846 patients with RA was recruited, of which 589 patients of working age at disease onset constituted the study population. Information on the socio-demographic, clinical, working and financial conditions of the patients was collected. Logistic regression analyses were used to identify factors associated with work capacity impairment. Results. The rate of work capacity impairment was 48.0% in RA patients with a mean disease duration of 60 months (interquartile range 14-134 months), including 11.7% leaving the labour force early, 33.6% working reduced hours and 2.7% changing job. Multivariable logistic regression analysis showed that reduced working hours was significantly related to current smoking [odds ratio (OR) 2.07 (95% CI 1.08, 3.97)], no insurance [OR 1.94 (95% CI 1.20, 3.12)], in manual labour [OR 2.66 (95% CI 1.68, 4.20)] and higher HAQ score [OR 2.22 (95% CI 1.36, 3.60)]. There was an association of current smoking [OR 3.75 (95% CI 1.54, 9.15)], in manual labour [OR 2.33 (95% CI 1.17, 4.64)], longer disease duration OR 1.01 (95% CI 1.00, 1.01)] and lower BMI [OR 0.90 (95% CI 0.82, 0.99)] with leaving the labour force early. Conclusion. There is a substantial impact of RA on the work capacity of patients in China. Social-demographic, disease- and work-related factors are all associated with work capacity impairment.
基金：
National Key Technology RD ProgramNational Key Technology R&D Program [2008BAI59B01]; Ministry of Health
第一作者单位：[1]Department of Rheumatology and Immunology, People’s Hospital,Peking University Health Science Center
共同第一作者：
通讯作者：
通讯机构：[1]Department of Rheumatology and Immunology, People’s Hospital,Peking University Health Science Center[*1]Department of Rheumatology, People’s Hospital, Peking University Health Science Center, No. 11 Xizhimen South Street, Western District, Beijing, China
推荐引用方式(GB/T 7714)：
Xiaoying Zhang,Rong Mu,Xiuru Wang,et al.The impact of rheumatoid arthritis on work capacity in Chinese patients: a cross-sectional study[J].RHEUMATOLOGY.2015,54(8):1478-1487.doi:10.1093/rheumatology/kev014.
APA：
Xiaoying Zhang,Rong Mu,Xiuru Wang,Chuanhui Xu,Tianjiao Duan...&Zhanguo Li.(2015).The impact of rheumatoid arthritis on work capacity in Chinese patients: a cross-sectional study.RHEUMATOLOGY,54,(8)
MLA：
Xiaoying Zhang,et al."The impact of rheumatoid arthritis on work capacity in Chinese patients: a cross-sectional study".RHEUMATOLOGY 54..8(2015):1478-1487
