单位：[1]Graduate School, Beijing University of Chinese Medicine, Beijing 100029, China[2]Department of Pediatrics, 3Institute of Clinical Medical Sciences, China-Japan Friendship Hospital, Beijing 100029, China[4]National Clinical Research Center for Respiratory Diseases, Beijing 100029, China[5]Department of Children’s Health Care, Beijing Chaoyang District Maternal and Child Health Care Hospital, Beijing 100026, China[6]International Medical Services, China-Japan Friendship Hospital, Beijing 100029, China
Background: Pediatric overweight/obesity has escalated to epidemic proportions worldwide. In this study, we aimed to assess the association of delivery mode and maternal age, both individually and interactively, with the risk of being overweight or obese among Chinese preschool children. Methods: We cross-sectionally recruited 1,123 preschool children from five kindergartens in Beijing. Data were collected by a pre-validated self-developed questionnaire. Overweight and obesity are defined according to the World Health Organization (WHO), International Obesity Task Force (IOTF), and China criteria, respectively. Results: Cesarean delivery was significantly associated with pediatric overweight/obesity under the WHO [adjusted odds ratio (aOR), 95% confidence interval (CI): 1.60, 1.12-2.29], IOTF (1.77, 1.23-2.53), and China (1.43, 1.06-1.94) criteria, respectively. Maternal age <28 years reached statistical significance under both WHO (1.69, 1.09-2.61) and IOTF (1.69, 1.09-2.61) criteria in predicting pediatric overweight/obesity. The interaction between cesarean delivery and maternal age <28 years was remarkably significant under the WHO (2.26, 1.10-4.67), IOTF (2.92, 1.43-5.96), and China (2.36, 1.24-4.50) criteria. Conclusions: Our findings indicate that the interaction between cesarean delivery and maternal age <28 years can remarkably increase the risk of overweight/obesity among Chinese preschool children.
基金：
National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [41571376, 81970042]; Fundamental Research Funds for the Central Universities and Research projects on biomedical transformation of China-Japan Friendship Hospital [PYBZ1812]
第一作者单位：[1]Graduate School, Beijing University of Chinese Medicine, Beijing 100029, China[2]Department of Pediatrics, 3Institute of Clinical Medical Sciences, China-Japan Friendship Hospital, Beijing 100029, China
通讯作者：
通讯机构：[2]Department of Pediatrics, 3Institute of Clinical Medical Sciences, China-Japan Friendship Hospital, Beijing 100029, China[5]Department of Children’s Health Care, Beijing Chaoyang District Maternal and Child Health Care Hospital, Beijing 100026, China[6]International Medical Services, China-Japan Friendship Hospital, Beijing 100029, China[*1]No.2 Yinghua East Street, Chaoyang District, Beijing 100029, China
推荐引用方式(GB/T 7714)：
Liu Shufang,Lei Jieping,Ma Jia,et al.Interaction between delivery mode and maternal age in predicting overweight and obesity in 1,123 Chinese preschool children[J].ANNALS of TRANSLATIONAL MEDICINE.2020,8(7):doi:10.21037/atm.2020.03.128.
APA：
Liu, Shufang,Lei, Jieping,Ma, Jia,Ma, Yanyan,Wang, Shunan...&Niu, Wenquan.(2020).Interaction between delivery mode and maternal age in predicting overweight and obesity in 1,123 Chinese preschool children.ANNALS of TRANSLATIONAL MEDICINE,8,(7)
MLA：
Liu, Shufang,et al."Interaction between delivery mode and maternal age in predicting overweight and obesity in 1,123 Chinese preschool children".ANNALS of TRANSLATIONAL MEDICINE 8..7(2020)
