单位：[1]Information Engineering College, Hubei University of Chinese Medicine, Wuhan, Hubei, China[2]Department of Pulmonary and Critical Care Medicine, Center of Respiratory Medicine, China-Japan Friendship Hospital, National Clinical Research Center for Respiratory Diseases, Beijing, China[3]Chinese PLA Center for Disease Control and Prevention, Beijing, China[4]Department of Global Health, School of Health Sciences, Wuhan University, Wuhan, Hubei, China[5]Department of Epidemiology, School of Public Health and Management, Binzhou Medical University, Yantai, Shandong, China[6]Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia
This study aims to examine the association between short-term exposures to PM1, PM2.5 and PM10 (particulate matter with aerodynamic diameters <= 1 mu m, <= 2.5 mu m and <= 10 mu m, respectively) and hospital admission for ischemic stroke in China. Daily counts of hospital admission for ischemic stroke were collected in 5 hospitals in China during November 2013 to October 2015. Daily concentrations of PM1, PM2.5 and PM10) were collected in 5 cities where the hospitals were located. A time-stratified casecrossover design was used to examine the hospital-specific PM-ischemic stroke association after controlling for potential confounders. Then the effect estimates were pooled using a random-effect metaanalysis. A total of 68,122 hospital admissions for ischemic stroke were identified from 5 hospitals during the study period. The pooled results showed that exposures to PM1, PM2.5 and PM10 were significantly associated with increased hospital admission for ischemic stroke on the current day and previous 1 day. The RRs (relative risk associated with per 10 mu g/m(3) increase in each pollutant) and 95%Cls (confidence intervals) for the cumulative effects of PM1, PM2.5 and PM10 on ischemic stroke during lag 0-1 days were 1.014 (1.005, 1.0023), 1.007 (1.000, 1.014) and 1.005 (1.001, 1.009), respectively. In total, 3.5%, 3.6% and 4.1% of hospital admissions for ischemic stroke could be attributable to PM1, PM2.5 and PM10, respectively. Exposures to ambient PM1, PM2.5 and PM10 pollution showed acute adverse effects on hospital admission for ischemic stroke. The health effects of PM1 should be considered by policy-makers. (C) 2019 Elsevier Ltd. All rights reserved.
基金：
Wuhan University [600460001]; Career Development Fellowship of Australian National Health and Medical Research Council (NHMRC)National Health and Medical Research Council of Australia [APP1107107, APP1163693]; Early Career Fellowship of NHMRCNational Health and Medical Research Council of Australia [APP1109193]
第一作者单位：[1]Information Engineering College, Hubei University of Chinese Medicine, Wuhan, Hubei, China
通讯作者：
通讯机构：[6]Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia[*1]Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC 3004, Australia.
推荐引用方式(GB/T 7714)：
Chen Lijun,Zhang Yongming,Zhang Wenyi,et al.Short-term effect of PM1 on hospital admission for ischemic stroke: A multi-city case-crossover study in China[J].ENVIRONMENTAL POLLUTION.2020,260:doi:10.1016/j.envpol.2019.113776.
APA：
Chen, Lijun,Zhang, Yongming,Zhang, Wenyi,Chen, Gongbo,Lu, Peng...&Li, Shanshan.(2020).Short-term effect of PM1 on hospital admission for ischemic stroke: A multi-city case-crossover study in China.ENVIRONMENTAL POLLUTION,260,
MLA：
Chen, Lijun,et al."Short-term effect of PM1 on hospital admission for ischemic stroke: A multi-city case-crossover study in China".ENVIRONMENTAL POLLUTION 260.(2020)
环境科学与生态学