单位：[1]State Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China.[2]Department of Obstetrics and Gynecology, China-Japan Friendship Hospital, Beijing 100029, China.
Early colonization of intestinal microbiota during the neonatal stage plays an important role on the development of intestinal immune system and nutrients absorption of the host. Compared to the normal birth weight (NBW) piglets, intrauterine growth restricted (IUGR) piglets have a different intestinal microbiota during their early life, which is related to maternal imprinting on intestinal microbial succession during gestation, at birth and via suckling. Imbalanced allocation of limited nutrients among fetuses during gestation could be one of the main causes for impaired intestinal development and microbiota colonization in neonatal IUGR piglets. In this review, we summarized the potential impact of maternal imprinting on the colonization of the intestinal microbiota in IUGR piglets, including maternal undernutrition, imbalanced allocation of nutrients among fetuses, as well as vertical microbial transmission from mother to offspring during gestation and lactation. At the same time, we give information about the current maternal nutritional strategies (mainly breastfeeding, probiotics and prebiotics) to help colonization of the advantageous intestinal microbiota for IUGR piglets.
基金：
Beijing Municipal Natural Science FoundationBeijing Natural Science Foundation [S170001]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [31630074, 31272449, 31902170]; National Key Research and Development Program of China [2016YFD0500506, 2018YDF0501002]; 111 ProjectMinistry of Education, China - 111 Project [B16044]; Jinxinnong Animal Science Developmental Foundation
第一作者单位：[1]State Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China.
通讯作者：
推荐引用方式(GB/T 7714)：
Jiang Lili,Feng Cuiping,Tao Shiyu,et al.Maternal imprinting of the neonatal microbiota colonization in intrauterine growth restricted piglets: a review[J].JOURNAL of ANIMAL SCIENCE and BIOTECHNOLOGY.2019,10(1):doi:10.1186/s40104-019-0397-7.
APA：
Jiang, Lili,Feng, Cuiping,Tao, Shiyu,Li, Na,Zuo, Bin...&Wang, Junjun.(2019).Maternal imprinting of the neonatal microbiota colonization in intrauterine growth restricted piglets: a review.JOURNAL of ANIMAL SCIENCE and BIOTECHNOLOGY,10,(1)
MLA：
Jiang, Lili,et al."Maternal imprinting of the neonatal microbiota colonization in intrauterine growth restricted piglets: a review".JOURNAL of ANIMAL SCIENCE and BIOTECHNOLOGY 10..1(2019)
农林科学