单位：[1]Capital Medical University, Beijing Friendship Hospital, Department of Nuclear Medicine,95, Yong An Road, Xi Cheng district, 100050 Beijing, People’s Republic of China医技科室影像中心核医学科首都医科大学附属北京友谊医院[2]Capital Medical University, Beijing Friendship Hospital, Radiology Department, 95,Yong An Road, Xi Cheng district, 100050 Beijing, People’s Republic of China医技科室影像中心放射科首都医科大学附属北京友谊医院
Purpose: The goal of this study is to investigate whether combined application of ultrasound and 99mTc-sestamibi SPECT/CT had the incremental value in accurately detecting parathyroid tissue in patients with SHPT over either method alone. Patients and methods: Sixty patients with SHPT on hemodialysis were evaluated preoperatively with parathyroid 99mTc-sestamibi SPECT/CT scintigraphy and ultrasound prior to parathyroidectomy. The sensitivity, specificity and accuracy of 99mTc-sestamibi SPECT/CT scintigraphy, ultrasound and combined application were determined respectively. Results: The sensitivity, specificity and accuracy of ultrasound were 81% (155/192), 47% (17/36) and 82% (172/228), respectively. The sensitivity, specificity and accuracy of 99mTc-sestamibi SPECT/CT were 85% (163/192), 58% (21/36) and 89% (184/228) respectively. The accuracy of 99mTc-sestamibi SPECT/CT in the diagnosis of parathyroid tissue in patients with SHPT is significantly higher than that of ultrasound. The sensitivity, specificity and accuracy of combined application of ultrasound and 99mTc-sestamibi SPECT/CT were 93% (178/192), 61% (22/36) and 97% (200/228). The sensitivity, specificity and accuracy of combined application of ultrasound and 99mTc-sestamibi SPECT/CT were higher than those of either ultrasound or 99mTc-sestamibi SPECT/CT. Conclusions: The combined application of ultrasound and 99mTc-sestamibi SPECT/CT had incremental value in accurately detecting parathyroid tissue in patients with SHPT over eithermethod alone. (C) 2015 Editions francaises de radiologie. Published by Elsevier Masson SAS. All rights reserved.
基金：
Beijing Excellent Talent [2014000021223ZK45]; Beijing Natural Science FoundationBeijing Natural Science Foundation [7152041]; Beijing health system high level technical personnel [2013-3-066]
第一作者单位：[1]Capital Medical University, Beijing Friendship Hospital, Department of Nuclear Medicine,95, Yong An Road, Xi Cheng district, 100050 Beijing, People’s Republic of China
通讯作者：
推荐引用方式(GB/T 7714)：
Yuan L. L.,Kan Y.,Ma D. Q.,et al.Combined application of ultrasound and SPECT/CT has incremental value in detecting parathyroid tissue in SHPT patients[J].DIAGNOSTIC and INTERVENTIONAL IMAGING.2016,97(2):219-225.doi:10.1016/j.diii.2015.08.007.
APA：
Yuan, L. L.,Kan, Y.,Ma, D. Q.&Yang, J. G..(2016).Combined application of ultrasound and SPECT/CT has incremental value in detecting parathyroid tissue in SHPT patients.DIAGNOSTIC and INTERVENTIONAL IMAGING,97,(2)
MLA：
Yuan, L. L.,et al."Combined application of ultrasound and SPECT/CT has incremental value in detecting parathyroid tissue in SHPT patients".DIAGNOSTIC and INTERVENTIONAL IMAGING 97..2(2016):219-225
