Glucose is an important molecule for metabolism. It is more actively taken up in tumor cells than in normal cells, thus making it possible to detect the tumor. Radiolabeled glucose derivates have been successfully employed for tumor imaging for several decades. This review focuses on the development of various radiolabeled glucose derivatives as tumor imaging probes with single photon emission computed tomography (SPECT) and positron emission tomography (PET) and discusses basic research data, current status and future prospects of this class of imaging agents.
基金:
National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21171024, 81101069]; Beijing Natural Science FoundationBeijing Natural Science Foundation [7112035]; Fundamental Research Funds for the Central UniversitiesFundamental Research Funds for the Central Universities [105566]; Beijing Nova ProgramBeijing Municipal Science & Technology Commission [xxhz201306]
第一作者单位:[1]Beijing Normal Univ, Coll Chem, Key Lab Radiopharmaceut, Minist Educ, Beijing 100875, Peoples R China
通讯作者:
通讯机构:[1]Beijing Normal Univ, Coll Chem, Key Lab Radiopharmaceut, Minist Educ, Beijing 100875, Peoples R China[*1]Beijing Normal Univ, Coll Chem, Beijing 100875, Peoples R China
推荐引用方式(GB/T 7714):
Liu T.,Zhang J.,Wang X.,et al.Radiolabeled Glucose Derivatives for Tumor Imaging Using SPECT and PET[J].CURRENT MEDICINAL CHEMISTRY.2014,21(1):24-34.
APA:
Liu, T.,Zhang, J.,Wang, X.,Yang, J.,Tang, Z.&Lu, J..(2014).Radiolabeled Glucose Derivatives for Tumor Imaging Using SPECT and PET.CURRENT MEDICINAL CHEMISTRY,21,(1)
MLA:
Liu, T.,et al."Radiolabeled Glucose Derivatives for Tumor Imaging Using SPECT and PET".CURRENT MEDICINAL CHEMISTRY 21..1(2014):24-34