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Ambulatory arterial stiffness index correlates with ambulatory pulse pressure but not dipping status in patients with grade 1/grade 2 essential hypertension

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单位: [1]China Japan Friendship Hosp, Dept Cardiol, Beijing 100029, Peoples R China [2]Peking Univ, Peoples Hosp, Dept Cardiol, Beijing 100871, Peoples R China [3]Shanghai Jiao Tong Univ, Sch Med, Ctr Epidemiol Studies & Clin Trials, Shanghai Inst Hypertens,Ruijin Hosp, Shanghai 200030, Peoples R China [4]Fudan Univ, Zhongshan Hosp, Dept Cardiol, Shanghai 200433, Peoples R China
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关键词: Ambulatory blood pressure monitoring ambulatory arterial stiffness index blood pressure variability morning blood pressure surge pulse pressure

摘要:
Objective: To evaluate the relationship between ambulatory arterial stiffness index (AASI) and other parameters derived from ambulatory blood pressure (BP) monitoring, including dipping status, in patients with grade 1/grade 2 hypertension. Methods: This retrospective analysis included baseline data from Chinese outpatients enrolled into a previous study, who had clinic diastolic BP of 90-109mmHg and systolic BP < 180 mmHg, had undergone 24-h ambulatory BP monitoring and routine blood chemistry investigations, and had estimated glomerular filtration rate (eGFR) data. Results: Out of 120 patients screened, 87 were included. No significant difference in 24-h AASI was found between dippers and nondippers. The 24-h AASI significantly correlated with age, systolic BP and pulse pressure, and inversely correlated with 24-h diastolic BP variation and eGFR. In dippers and nondippers, AASI correlated with daytime pulse pressure, daytime diastolic BP variation and eGFR; in nondippers, AASI also correlated with 24-h systolic BP and 24-h pulse pressure. The 24-h AASI was significantly associated with 24-h pulse pressure and daytime pulse pressure. Conclusion: In patients with grade 1/grade 2 essential hypertension, AASI shows a significant correlation with ambulatory pulse pressure.

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出版当年[2013]版:
大类 | 4 区 医学
小类 | 4 区 医学:研究与实验 4 区 药学
最新[2025]版:
大类 | 4 区 医学
小类 | 4 区 医学:研究与实验 4 区 药学
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出版当年[2012]版:
Q4 PHARMACOLOGY & PHARMACY Q4 MEDICINE, RESEARCH & EXPERIMENTAL
最新[2023]版:
Q4 MEDICINE, RESEARCH & EXPERIMENTAL Q4 PHARMACOLOGY & PHARMACY

影响因子: 最新[2023版] 最新五年平均[2021-2025] 出版当年[2012版] 出版当年五年平均[2008-2012] 出版前一年[2011版] 出版后一年[2013版]

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第一作者单位: [1]China Japan Friendship Hosp, Dept Cardiol, Beijing 100029, Peoples R China
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通讯机构: [1]China Japan Friendship Hosp, Dept Cardiol, Beijing 100029, Peoples R China [*1]China Japan Friendship Hosp, Dept Cardiol, 2 Yinghua Dongjie, Beijing 100029, Peoples R China
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