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Acyl glycosides with rare beta-D-apiofuranosyl-beta-D-glucopyranosyl-beta-D-apiofuranosyl from Erycibe hainanesis

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单位: [1]Peking Union Med Coll, Inst Mat Med, State Key Lab Bioact Subst & Funct Nat Med, Beijing 100050, Peoples R China [2]Chinese Acad Med Sci, Beijing 100050, Peoples R China [3]Dalian Polytech Univ, Dalian 116034, Liaoning, Peoples R China [4]China Japan Friendship Hosp, Dept Pharm, Beijing, Peoples R China
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关键词: beta-D-Apiofuranosyl-beta-D-glucopyranosyl-beta-D-apiofuranosyl Acyl glycoside Convolvulaceae Erycibe hainanesis Hepatoprotective activity

摘要:
Three new acyl glycosides with rare beta-D-apiofuranosyl-(1 -> 2)-[beta-D-apiofuranosyl-(1 -> 6)]-beta-D-glucopyranosyl moieties, 2-O-[2,6-O-bis(5-O-syringoyl-beta-D-apiofuranosyl)-beta-D-glucopyranosyl]-isopropyl alcohol (1), 1-O-[2,6-O-bis(5-O-syringoyl-beta-D-apiofuranosyl)-beta-D-glucopyranosyl]-isoamyl alcohol (2), and 1-O-[2,6-O-bis(5-O-vanilloyl-beta-D-apiofuranosyl)-beta-D-glucopyranosyl]-3,4,5-trimethoxyphenol (3) were obtained from Erycibe hainanesis. Their structures were determined by UV, IR, HRESIMS, D-1 and D-2 NMR data, and by chemical methods. Compounds 1-3 were evaluated against D-galactosamine induced toxicity in WB-F344 rat hepatic epithelial stem-like cells, and compounds 1 and 3 showed moderate hepatoprotective activities. (C) 2013 Published by Elsevier Ltd.

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出版当年[2012]版:
大类 | 4 区 化学
小类 | 3 区 应用化学 4 区 生化与分子生物学 4 区 有机化学
最新[2025]版:
大类 | 3 区 化学
小类 | 3 区 应用化学 3 区 有机化学 4 区 生化与分子生物学
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出版当年[2011]版:
Q2 CHEMISTRY, APPLIED Q3 BIOCHEMISTRY & MOLECULAR BIOLOGY Q3 CHEMISTRY, ORGANIC
最新[2023]版:
Q2 CHEMISTRY, APPLIED Q2 CHEMISTRY, ORGANIC Q3 BIOCHEMISTRY & MOLECULAR BIOLOGY

影响因子: 最新[2023版] 最新五年平均[2021-2025] 出版当年[2011版] 出版当年五年平均[2007-2011] 出版前一年[2010版] 出版后一年[2012版]

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第一作者单位: [1]Peking Union Med Coll, Inst Mat Med, State Key Lab Bioact Subst & Funct Nat Med, Beijing 100050, Peoples R China [2]Chinese Acad Med Sci, Beijing 100050, Peoples R China
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通讯机构: [1]Peking Union Med Coll, Inst Mat Med, State Key Lab Bioact Subst & Funct Nat Med, Beijing 100050, Peoples R China [2]Chinese Acad Med Sci, Beijing 100050, Peoples R China
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