单位:[1]China-Japan Friendship Hospital, Beijing, China[2]Peking University Peoples’ Hospital, Beijing, China[3]Shanghai Jiaotong University Affiliated Sixth People’s Hospital, Shanghai, China[4]Sun Yat-sen University Third Hospital, Guangzhou, China中山大学附属第三医院[5]Chinese PLA General Hospital, Beijing, China[6]First Affiliated Hospital, Chinese Medical University, Liaoling, China[7]Shanxi Province People’s Hospital, Shanxi, China[8]West China Hospital, Sichuan University, Sichuan, China四川大学华西医院[9]Xijing Hospital, Fourth Military Medical University, Shaanxi, China[10]Affiliated Drum Tower Hospital of Nanjing University Medical School, Jiangsu, China[11]Xinjiang Uygur Autonomous Region’s Hospital, Xinjiang, China[12]Fujian Provincial Hospital, Fujiang, China[13]Qilu Hospital, Qilu Hospital of Shandong University, Shandong, China[14]Peking University First Hospital, Beijing, China[15]Henan Province People’s Hospital, Henan, China[16]Second Affiliated Hospital of Harbin Medical University, Heilongjiang, China[17]Xiangya Second Hospital, Hunan, China[18]Peking Union Medical College, Beijing, China[19]Tulane University School of Public Health and Tropical Medicine, New Orleans, LA
Background-Because of rapid change in lifestyle risk factors, cardiovascular disease has become the leading cause of death in China. We sought to estimate the national levels of serum lipids and lipoproteins among the Chinese adult population. Methods and Results-We conducted a cross-sectional study in a nationally representative sample of 46 239 adults aged >= 20 years. Fasting serum total, high-density lipoprotein, and low-density lipoprotein cholesterol and triglycerides were measured by standard methods. The age-standardized estimates of total, high-density lipoprotein, and low-density lipoprotein cholesterol and triglycerides were 4.72 (95% confidence interval, 4.70-4.73), 1.30 (1.29-1.30), 2.68 (2.67-2.70), and 1.57 (1.55-1.58) mmol/L, respectively, in the Chinese adult population. In addition, 22.5% (21.8-23.3%) or 220.4 million (212.1-228.8) Chinese adults had borderline high total cholesterol (5.18-6.21 mmol/L), and 9.0% (8.5-9.5%) or 88.1 million (83.4-92.8) had high total cholesterol (> 6.22 mmol/L). The population estimates for borderline high (3.37-4.13 mmol/L), high (4.14-4.91 mmol/L), and very high (>= 4.92 mmol/L) low-density lipoprotein cholesterol were 13.9% (13.3-14.5%) or 133.5 million (127.0-140.1), 3.5% (3.3-3.8%) or 33.8 million (31.2-36.5), and 3.0% (2.8-3.3%) or 29.0 million (26.3-31.8) persons, respectively. In addition, 22.3% (21.6-23.1%) or 214.9 million (207.0-222.8) persons had low high-density lipoprotein cholesterol (<1.04 mmol/L). The awareness, treatment, and control of borderline high or high total cholesterol were 11.0%, 5.1%, and 2.8%, respectively, in the Chinese adult population. Conclusions-Serum total and low-density lipoprotein cholesterol levels were high and increasing in the Chinese population. Without effective intervention, atherosclerotic cardiovascular diseases may soar in the near future in China. (Circulation. 2012;125:2212-2221.)
基金:
Chinese Medical Association Foundation; Chinese Diabetes Society
Yang Wenying,Xiao Jianzhong,Yang Zhaojun,et al.Serum Lipids and Lipoproteins in Chinese Men and Women[J].CIRCULATION.2012,125(18):2212-2221.doi:10.1161/CIRCULATIONAHA.111.065904.
APA:
Yang, Wenying,Xiao, Jianzhong,Yang, Zhaojun,Ji, Linong,Jia, Weiping...&He, Jiang.(2012).Serum Lipids and Lipoproteins in Chinese Men and Women.CIRCULATION,125,(18)
MLA:
Yang, Wenying,et al."Serum Lipids and Lipoproteins in Chinese Men and Women".CIRCULATION 125..18(2012):2212-2221